Literature DB >> 1492365

V(D)J recombination gets a break.

M Gellert1.   

Abstract

The diversity of immunoglobulins and T cell receptors is largely due to the assembly of functional genes from separate segments. The mechanism by which these gene fragments are joined is starting to be deciphered, with broken DNA molecules that may be intermediates in the reaction providing a new clue.

Mesh：

Year:  1992        PMID： 1492365     DOI： 10.1016/0168-9525(92)90322-u

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  11 in total

1.  A novel chromodomain protein, pdd3p, associates with internal eliminated sequences during macronuclear development in Tetrahymena thermophila.

Authors:  M A Nikiforov; M A Gorovsky; C D Allis
Journal:  Mol Cell Biol       Date:  2000-06       Impact factor: 4.272

2.  Activation of V(D)J recombination induces the formation of interlocus joints and hybrid joints in scid pre-B-cell lines.

Authors:  S Lew; D Franco; Y Chang
Journal:  Mol Cell Biol       Date:  2000-10       Impact factor: 4.272

3.  Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product.

Authors:  P H Domer; S S Fakharzadeh; C S Chen; J Jockel; L Johansen; G A Silverman; J H Kersey; S J Korsmeyer
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205

4.  Formation of coding joints in V(D)J recombination-inducible severe combined immune deficient pre-B cell lines.

Authors:  Y Chang; M L Brown
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-05       Impact factor: 11.205

5.  Mechanisms of overlap formation in nonhomologous DNA end joining.

Authors:  P Pfeiffer; S Thode; J Hancke; W Vielmetter
Journal:  Mol Cell Biol       Date:  1994-02       Impact factor: 4.272

6.  Programmed DNA rearrangement of a cyanobacterial hupL gene in heterocysts.

Authors:  C D Carrasco; J A Buettner; J W Golden
Journal:  Proc Natl Acad Sci U S A       Date:  1995-01-31       Impact factor: 11.205

7.  Excision of micronuclear-specific DNA requires parental expression of pdd2p and occurs independently from DNA replication in Tetrahymena thermophila.

Authors:  M A Nikiforov; J F Smothers; M A Gorovsky; C D Allis
Journal:  Genes Dev       Date:  1999-11-01       Impact factor: 11.361

Review 8.  Illegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy.

Authors:  Masahiro Onozawa; Peter D Aplan
Journal:  Genes Chromosomes Cancer       Date:  2012-02-15       Impact factor: 5.006

9.  Recombination-dependent DNA replication stimulated by double-strand breaks in bacteriophage T4.

Authors:  K N Kreuzer; M Saunders; L J Weislo; H W Kreuzer
Journal:  J Bacteriol       Date:  1995-12       Impact factor: 3.490

Review 10.  The SCID mouse: relevance as an animal model system for studying human disease.

Authors:  E A Hendrickson
Journal:  Am J Pathol       Date:  1993-12       Impact factor: 4.307
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