Literature DB >> 1492096

The superfamily of UvrA-related ATPases includes three more subunits of putative ATP-dependent nucleases.

E V Koonin1, A E Gorbalenya.   

Abstract

It is demonstrated that the amino acid sequences of the products of E. coli genes sbcC and prrC, and bacteriophage P2 gene old encompass the four conserved motifs typical of the superfamily of UvrA-related ATPases. A more pronounced statistically significant similarity was revealed between SbcC protein, bacteriophage T4 endonuclease component gp46 and bacteriophage T5 protein D13. It is suggested that the newly identified members of the superfamily might all be ATPase components of the respective nucleases, and that the reactions catalyzed by these enzymes are probably ATP dependent.

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Year:  1992        PMID: 1492096

Source DB:  PubMed          Journal:  Protein Seq Data Anal        ISSN: 0931-9506


  9 in total

Review 1.  Mechanisms of genome propagation and helper exploitation by satellite phage P4.

Authors:  B H Lindqvist; G Dehò; R Calendar
Journal:  Microbiol Rev       Date:  1993-09

2.  The old exonuclease of bacteriophage P2.

Authors:  H Myung; R Calendar
Journal:  J Bacteriol       Date:  1995-02       Impact factor: 3.490

3.  Toprim--a conserved catalytic domain in type IA and II topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins.

Authors:  L Aravind; D D Leipe; E V Koonin
Journal:  Nucleic Acids Res       Date:  1998-09-15       Impact factor: 16.971

Review 4.  The Macromolecular Machines that Duplicate the Escherichia coli Chromosome as Targets for Drug Discovery.

Authors:  Jon M Kaguni
Journal:  Antibiotics (Basel)       Date:  2018-03-14

5.  Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.

Authors:  Carl J Schiltz; April Lee; Edward A Partlow; Christopher J Hosford; Joshua S Chappie
Journal:  Nucleic Acids Res       Date:  2019-09-26       Impact factor: 16.971

6.  The full-length structure of Thermus scotoductus OLD defines the ATP hydrolysis properties and catalytic mechanism of Class 1 OLD family nucleases.

Authors:  Carl J Schiltz; Myfanwy C Adams; Joshua S Chappie
Journal:  Nucleic Acids Res       Date:  2020-03-18       Impact factor: 16.971

7.  A putative mobile genetic element carrying a novel type IIF restriction-modification system (PluTI).

Authors:  Feroz Khan; Yoshikazu Furuta; Mikihiko Kawai; Katarzyna H Kaminska; Ken Ishikawa; Janusz M Bujnicki; Ichizo Kobayashi
Journal:  Nucleic Acids Res       Date:  2010-01-13       Impact factor: 16.971

8.  A novel dimerization motif in the C-terminal domain of the Thermus thermophilus DEAD box helicase Hera confers substantial flexibility.

Authors:  Dagmar Klostermeier; Markus G Rudolph
Journal:  Nucleic Acids Res       Date:  2008-12-02       Impact factor: 16.971

9.  Comprehensive analysis of the HEPN superfamily: identification of novel roles in intra-genomic conflicts, defense, pathogenesis and RNA processing.

Authors:  Vivek Anantharaman; Kira S Makarova; A Maxwell Burroughs; Eugene V Koonin; L Aravind
Journal:  Biol Direct       Date:  2013-06-15       Impact factor: 4.540

  9 in total

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