Literature DB >> 1491626

Vitamin C--the primate fertility factor?

J Millar1.   

Abstract

The loss of the ability of primates and man to synthesise ascorbic acid (vitamin C) is usually seen as an evolutionary accident, with no benefit to the species. This paper argues that the loss of this biosynthetic ability has allowed vitamin C to act as a 'fertility factor' in primate societies. It is argued that the requirement for vitamin C increases with age, and so in times of food shortages the older members of society suffer higher mortality than the younger. This reduces the median age of the population towards the younger and most fertile members, and so enables the population to regrow rapidly when food resources are restored.

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Year:  1992        PMID: 1491626     DOI: 10.1016/0306-9877(92)90019-9

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  6 in total

1.  Ascorbic acid supplement during luteal phase in IVF.

Authors:  Georg Griesinger; Katharina Franke; Cordelia Kinast; Alexandra Kutzelnigg; Sandra Riedinger; Sandor Kulin; Steven G Kaali; Wilfried Feichtinger
Journal:  J Assist Reprod Genet       Date:  2002-04       Impact factor: 3.412

2.  Chromium-VI arrests cell cycle and decreases granulosa cell proliferation by down-regulating cyclin-dependent kinases (CDK) and cyclins and up-regulating CDK-inhibitors.

Authors:  Jone A Stanley; JeHoon Lee; Thamizh K Nithy; Joe A Arosh; Robert C Burghardt; Sakhila K Banu
Journal:  Reprod Toxicol       Date:  2011-05-20       Impact factor: 3.143

3.  The Graafian follicle is a site of L-ascorbate accumulation.

Authors:  T Paszkowski; R N Clarke
Journal:  J Assist Reprod Genet       Date:  1999-01       Impact factor: 3.412

Review 4.  Vitamin C: update on physiology and pharmacology.

Authors:  J Mandl; A Szarka; G Bánhegyi
Journal:  Br J Pharmacol       Date:  2009-06-05       Impact factor: 8.739

5.  Assessment of the luteal phase in stimulated and substituted cycles.

Authors:  H M Fatemi
Journal:  Facts Views Vis Obgyn       Date:  2009

6.  Glut-1 explains the evolutionary advantage of the loss of endogenous vitamin C-synthesis: The electron transfer hypothesis.

Authors:  Tabea C Hornung; Hans-Konrad Biesalski
Journal:  Evol Med Public Health       Date:  2019-08-28
  6 in total

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