Literature DB >> 1491339

Physical and lubrication properties of magnesium stearate.

U I Leinonen1, H U Jalonen, P A Vihervaara, E S Laine.   

Abstract

The lubrication properties of two commercial-grade magnesium stearates were studied. Their moisture contents and crystal structures were similar. There were minor differences in their fatty acid composition, but the differences did not affect the lubrication properties. The lubrication properties correlated with particle size distributions and specific surface area. The effect of these parameters was further studied with unmilled and milled chemically pure magnesium stearate. Milling decreased the particle size and increased the specific surface area. In both cases, the batch with a smaller particle size and larger specific surface area had considerably better lubricity.

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Year:  1992        PMID: 1491339     DOI: 10.1002/jps.2600811214

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  2 in total

1.  Quality-by-Design II: Application of Quantitative Risk Analysis to the Formulation of Ciprofloxacin Tablets.

Authors:  H Gregg Claycamp; Ravikanth Kona; Raafat Fahmy; Stephen W Hoag
Journal:  AAPS PharmSciTech       Date:  2015-07-23       Impact factor: 3.246

2.  Ionization states in the microenvironment of solid dosage forms: effect of formulation variables and processing.

Authors:  Ramprakash Govindarajan; Andrey Zinchuk; Bruno Hancock; Evgenyi Shalaev; Raj Suryanarayanan
Journal:  Pharm Res       Date:  2006-08-24       Impact factor: 4.200

  2 in total

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