Relation between psychometric tests and quantitative topographic EEG in pharmacology.

Both, psychometric tests and quantitative pharmaco-EEG are accepted as necessary tools in different fields of pharmacology. But using these methods separately, none is able to forward informations about the behavioral performance and the central nervous demand simultaneously. The solution of this problem is a complex psychophysiological set-up. Till today such complex measurement set-ups are a rarity. The main reason is the impossibility of EEG recordings during psychometric tests without different artefacts. In the present paper we demonstrate by using our own CATEEM-System in connection with the IBIS-Psychometry-system the possibility to get artefact free EEG recordings during psychometric test conditions. The different mental loads at different tests are producing a graduated increase in the delta and theta frequency range of the EEG of the fronto-temporal region and the occipital region of the cortex. During the tests a decrease of alpha-activity is seen generally. These effects can be described quantitatively as the topographical distribution of frequency changes. The present data are in line with the knowledge about the functional and anatomical structure of the human brain.