Literature DB >> 14906

The activity and distribution of gamma-glutamyl transpeptidase (y-GT) in human foetal organs.

N Fleming, P Groscurth, G S Kistler.   

Abstract

The activity and distribution of y-GT was investigated in a number of organs from human foetuses aged from 14 to 24 weeks post menstruationem. Over this period, enzyme activity increased in the kidney, pancreas and thymus, but decreased in the small intestine. No trend could be established for the liver, although activity was high. In the lung, spleen, brain and adrenals, y-GT was either detectable at very low levels or could not be demonstrated. The possible relationship between y-GT activity in some human tumours and the enzyme level in the corresponding foetal organs is discussed.

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Year:  1977        PMID: 14906     DOI: 10.1007/BF00567225

Source DB:  PubMed          Journal:  Histochemistry        ISSN: 0301-5564


  13 in total

1.  HISTOCHEMICAL AND BIOCHEMICAL INVESTIGATIONS OF GAMMA-GLUTAMYL TRANSPEPTIDASE IN THE TISSUES OF MAN AND LABORATORY RODENTS.

Authors:  Z ALBERT; J ORLOWSKA; M ORLOWSKI; A SZEWCZUK
Journal:  Acta Histochem       Date:  1964-05-30       Impact factor: 2.479

2.  GAMMA-GLUTAMYL TRANSPEPTIDASE IN CANCERS OF DIFFERENT HUMAN ORGANS.

Authors:  Z ALBERT
Journal:  Nature       Date:  1965-01-23       Impact factor: 49.962

3.  Histochemistry of gamma-glutamyl transpeptidase in rat liver during aflatoxin B1-induced carcinogenesis.

Authors:  M M Kalengayi; G Ronchi; V J Desmet
Journal:  J Natl Cancer Inst       Date:  1975-09       Impact factor: 13.506

4.  Role of gamma-glutamyl transpeptidase activity in the diagnosis of hepatobiliary disease.

Authors:  D M Goldberg; J V Martin
Journal:  Digestion       Date:  1975       Impact factor: 3.216

5.  On the cause of the increased activity of alkaline phosphatase and gamma-glutamyl transpeptidase in serum of patients with liver metastases.

Authors:  K F Aronsen; I Hägerstrand; J G Nordén; B Pihl
Journal:  Acta Chir Scand       Date:  1969

6.  A kinetic photometric method for serum gamma-glutamyl transpeptidase.

Authors:  G Szasz
Journal:  Clin Chem       Date:  1969-02       Impact factor: 8.327

7.  Histochemical and ultrastructural demonstration of gamma-glutamyl transpeptidase activity.

Authors:  A M Rutenburg; H Kim; J W Fischbein; J S Hanker; H L Wasserkrug; A M Seligman
Journal:  J Histochem Cytochem       Date:  1969-08       Impact factor: 2.479

8.  The gamma-glutamyl cycle: a possible transport system for amino acids.

Authors:  M Orlowski; A Meister
Journal:  Proc Natl Acad Sci U S A       Date:  1970-11       Impact factor: 11.205

9.  Histochemical demonstration of gamma-glutamyltranspeptidase in rat liver after portacaval anastomosis.

Authors:  E Müller; J P Colombo; E Peheim; J Bircher
Journal:  Experientia       Date:  1974-10-15

10.  Demonstration of gamma-glutamyl transpeptidase activity in human jejunal mucosa.

Authors:  E Greenberg; E E Wollaeger; G A Fleisher; G W Engstrom
Journal:  Clin Chim Acta       Date:  1967-04       Impact factor: 3.786

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  5 in total

1.  Differentiation of metanephric tubules following a short transfilter induction pulse.

Authors:  Eero Lehtonen; Hannu Jalanko; Liisa Laitinen; Aaro Miettinen; Peter Ekblom; Lauri Saxén
Journal:  Wilehm Roux Arch Dev Biol       Date:  1983-05

2.  The activity and distribution of gamma-glutamyl transpeptidase (y-GT) in human lung cancers serially transplanted in nude mice.

Authors:  P Groscurth; N Fleming; G S Kistler
Journal:  Histochemistry       Date:  1977-08-01

Review 3.  gamma-Glutamyltranspeptidase: a tumour cell marker with a pharmacological function.

Authors:  M Vanderlaan; W Phares
Journal:  Histochem J       Date:  1981-09

Review 4.  Cytochemistry of membrane proteases.

Authors:  R Gossrau
Journal:  Histochem J       Date:  1985-07

5.  Mechanism of biosynthesis of methylsulfones from PCBs and related compounds.

Authors:  T Mio; K Sumino
Journal:  Environ Health Perspect       Date:  1985-02       Impact factor: 9.031

  5 in total

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