Literature DB >> 148952

[Effect of guanidine dderivatives on choline acetylase and acetylcholinesterase of the rabbit brain].

M Matsumoto, M Fujiwara, A Mori, Y Robin.   

Abstract

The effects of 14 guanidino compounds on the activity of rabbit brain choline acetyltransferase (CAT) and acetylcholine esterase (ACE) have been studied, comparatively with that of pentylentetrazol. No guanidino compound examined nor pentylentetrazol had an effect on CAT activity. 4 of them showed a moderate inhibitory effect on ACE, of the same order of magnitude as that of pentylentetrazol, but significantly lower than that of the specific inhibitors eserine and mytelase.

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Year:  1977        PMID: 148952

Source DB:  PubMed          Journal:  C R Seances Soc Biol Fil        ISSN: 0037-9026


  2 in total

Review 1.  Biochemistry and neurotoxicology of guanidino compounds. History and recent advances.

Authors:  A Mori
Journal:  Pavlov J Biol Sci       Date:  1987 Jul-Sep

2.  Effects of GABAmimetics on electrocorticographic spike discharges induced by guanidinoethanesulfonic acid (amidino-taurine) in the rat.

Authors:  I Yokoi; H Kabuto; A Mori
Journal:  Neurochem Res       Date:  1993-04       Impact factor: 3.996

  2 in total

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