| Literature DB >> 1489102 |
H J Kim1, T J Balcezak, S J Nathin, H F McMullen, D E Hansen.
Abstract
We have developed a continuous spectrophotometric assay for S-adenosylmethionine synthetase and, using this assay, have examined the interaction of five potential inhibitors with the E. coli enzyme. S-Vinylhomocysteine and S-allylhomocysteine were found to be substrates, while S-(methanethio)cysteine and S-(methanethio)homocysteine were found to be competitive inhibitors. S-Cyanohomocysteine is neither a substrate nor an inhibitor.Entities:
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Year: 1992 PMID： 1489102 DOI： 10.1016/0003-2697(92)90501-w
Source DB: PubMed Journal: Anal Biochem ISSN： 0003-2697 Impact factor: 3.365