Literature DB >> 148823

[Electron microscopical findings of the myocardium in Fallot's disease and of the ventricular septal defects (author's transl)].

H David, D Oldag, B Schubel, H Warnke, D Behrisch.   

Abstract

Ultrastructural quantitative and qualitative investigations of the myocardium of 7 children with Fallot's disease and 3 children with a ventricular septal defect (VSD) have shown bizarre nuclei and a slight increase in the myofibril share of the volume (Fallot's disease: 51.22%; VSD: 56.85%). This may be interpreted as a sign of a cellular hypertrophy. The mitochondria have a proportion of 35.07% and 33.75%, respectively. The glycogen content is relatively high. The lipofuscin bodies originate mainly from mitochondria having a percentage of 1.43 and 1.67, respectively. Particular signs of a lesion could not be observed. From the ultrastructural findings on the morphology of heart muscle cells it can be deduced that operations of vitia may be safely carried out.

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Year:  1978        PMID: 148823

Source DB:  PubMed          Journal:  Zentralbl Allg Pathol        ISSN: 0044-4030


  1 in total

1.  Hereditary mitochondrial hypertrophic cardiomyopathy with mitochondrial myopathy of skeletal muscle, congenital cataract and lactic acidosis.

Authors:  G J van Ekeren; A M Stadhouders; G J Egberink; R C Sengers; O Daniëls; K Kubat
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1987
  1 in total

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