Literature DB >> 14872265

[Corneal infiltrates and ulcers. A retrospective study of 239 eyes].

B Neumaier-Ammerer1, U Stolba, S Binder, H Feichtinger.   

Abstract

PURPOSE: In our outpatient service the number of corneal infiltrates and ulcers associated with contact lens wear in young patients increased during the last years. Therefore we evaluated all patients with keratitis regarding to the reason. PATIENTS AND METHODS: From January 1999 to August 2000 the medical charts of 210 consecutive patients and 239 eyes were reviewed. We evaluated the percentage of contact lens wearers. Patient age, localisation and number of infiltrates, bacteria and healing results were also evaluated.
RESULTS: In 134 of 239 eyes (56%) keratitis was caused by contact lenses, 127 eyes (53%) with soft lenses. The mean age of soft contact lens wearing patients was 28,2 +/-13,0 years. Mean age in other reasons was 46,0 +/-22,5 years. 71% (170 eyes) had single central infiltrates, 19% (45 eyes) multiple peripheral infiltrates and 10% (24 eyes) corneal ulcers. Bacteria were found in 33% (78 eyes). The most frequent isolated bacteria in non contact lens induced keratitis was staphylococcus aureus (22 eyes). In those eyes with soft contact lenses we found mostly gram negative bacteria such as serratia spp. (6 eyes), pseudomonas spp. (6 eyes), stenotrophomonas maltophilia (6 eyes) and klebsiella oxytoca (5 eyes). 20% (26 of 127 eyes) of contact lens induced corneal infection healed with a scar.
CONCLUSION: Our analysis shows, that the major part of keratitis was induced by soft contact lenses. One fifth of these very young patients retained a corneal scar. There is a higher risk to suffer a keratitis when using soft contact lenses. This should influence especially patients information regarding choice and use of soft contact lenses.

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Year:  2004        PMID: 14872265     DOI: 10.1007/s00347-003-0896-x

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  14 in total

1.  Extended wear contact lens related bacterial keratitis.

Authors:  K F Tabbara; H F El-Sheikh; B Aabed
Journal:  Br J Ophthalmol       Date:  2000-03       Impact factor: 4.638

2.  Ulcerative keratitis associated with contact lens wear.

Authors:  E Alfonso; S Mandelbaum; M J Fox; R K Forster
Journal:  Am J Ophthalmol       Date:  1986-04-15       Impact factor: 5.258

Review 3.  Contact lens-related microbial keratitis: Part II: Pathophysiology.

Authors:  T J Liesegang
Journal:  Cornea       Date:  1997-05       Impact factor: 2.651

4.  Bacterial keratitis: a prospective clinical and microbiological study.

Authors:  F Schaefer; O Bruttin; L Zografos; Y Guex-Crosier
Journal:  Br J Ophthalmol       Date:  2001-07       Impact factor: 4.638

Review 5.  The role of Serratia marcescens in soft contact lens associated ocular infections. A review.

Authors:  P A Parment
Journal:  Acta Ophthalmol Scand       Date:  1997-02

6.  Bacterial invasion of corneal epithelial cells.

Authors:  V Vallas; F Stapleton; M D Willcox
Journal:  Aust N Z J Ophthalmol       Date:  1999 Jun-Aug

7.  Keratoconjunctivitis and soft contact lens solutions.

Authors:  P S Binder; D M Rasmussen; M Gordon
Journal:  Arch Ophthalmol       Date:  1981-01

8.  Gram-negative bacteria can induce contact lens related acute red eye (CLARE) responses.

Authors:  B A Holden; D La Hood; T Grant; J Newton-Howes; C Baleriola-Lucas; M D Willcox; D F Sweeney
Journal:  CLAO J       Date:  1996-01

9.  Corneal ulcers associated with contact lens wear.

Authors:  P G Galentine; E J Cohen; P R Laibson; C P Adams; R Michaud; J J Arentsen
Journal:  Arch Ophthalmol       Date:  1984-06

10.  Incidence of ulcerative keratitis in a defined population from 1950 through 1988.

Authors:  J C Erie; M P Nevitt; D O Hodge; D J Ballard
Journal:  Arch Ophthalmol       Date:  1993-12
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  3 in total

1.  [Classification of biomedical research reports as a reference for evidence-based medicine in ophthalmology. A survey considering as example the journal Der Ophthalmologe].

Authors:  H P N Scholl; M Fleckenstein; T U Krohne; F G Holz
Journal:  Ophthalmologe       Date:  2005-12       Impact factor: 1.059

2.  Microbiological findings and predisposing risk factors in corneal ulcers.

Authors:  Verena Prokosch; Zisis Gatzioufas; Solon Thanos; Tobias Stupp
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-11-25       Impact factor: 3.117

3.  Contact Lens Induced Corneal Ulcer Management in a Tertiary Eye Unit in Oman - A descriptive study.

Authors:  Rikin Shah; Manali Shah; Rajiv Khandekar; Abdulatif Al-Raisi
Journal:  Sultan Qaboos Univ Med J       Date:  2008-11
  3 in total

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