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Literature DB >> 14871459

Amphoterin as an extracellular regulator of cell motility: from discovery to disease.

Abstract

Amphoterin is a ubiquitous and highly conserved protein previously considered solely as a chromatin-associated, nuclear molecule. Amphoterin is released into the extracellular space by various cell types, and plays an important role in the regulation of cell migration, differentiation, tumorigenesis and inflammation. This paper reviews recent research on the mechanistic background underlying the biology of secreted amphoterin, with an emphasis on the role of amphoterin as an autocrine/paracrine regulator of cell migration.

Entities: Disease Gene

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Year: 2004 PMID： 14871459 DOI： 10.1111/j.1365-2796.2003.01301.x

Source DB: PubMed Journal: J Intern Med ISSN： 0954-6820 Impact factor: 8.989

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Cited

45 in total

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Journal: Inflammation Date: 2012-02 Impact factor: 4.092

Review 2. Scientific and clinical challenges in sepsis.

Authors: Luis Ulloa; Michael Brunner; Laura Ramos; Edwin A Deitch
Journal: Curr Pharm Des Date: 2009 Impact factor: 3.116

3. Axonal amphoterin mRNA is regulated by translational control and enhances axon outgrowth.

Authors: Tanuja T Merianda; Jennifer Coleman; Hak Hee Kim; Pabitra Kumar Sahoo; Cynthia Gomes; Paul Brito-Vargas; Heikki Rauvala; Armin Blesch; Soonmoon Yoo; Jeffery L Twiss
Journal: J Neurosci Date: 2015-04-08 Impact factor: 6.167

4. HMGB1 is an endogenous immune adjuvant released by necrotic cells.

Authors: Patrizia Rovere-Querini; Annalisa Capobianco; Paola Scaffidi; Barbara Valentinis; Federica Catalanotti; Marta Giazzon; Ingrid E Dumitriu; Susanne Müller; Matteo Iannacone; Catia Traversari; Marco E Bianchi; Angelo A Manfredi
Journal: EMBO Rep Date: 2004-07-23 Impact factor: 8.807

5. Co-treatment with deoxycholic acid and azoxymethane accelerates secretion of HMGB1 in IEC6 intestinal epithelial cells.

Authors: K Fujii; Y Luo; T Sasahira; A Denda; H Ohmori; H Kuniyasu
Journal: Cell Prolif Date: 2009-07-06 Impact factor: 6.831

Amphoterin as an extracellular regulator of cell motility: from discovery to disease.

1. HMGB1 increases permeability of the endothelial cell monolayer via RAGE and Src family tyrosine kinase pathways.

Review 2. Scientific and clinical challenges in sepsis.

3. Axonal amphoterin mRNA is regulated by translational control and enhances axon outgrowth.

4. HMGB1 is an endogenous immune adjuvant released by necrotic cells.

5. Co-treatment with deoxycholic acid and azoxymethane accelerates secretion of HMGB1 in IEC6 intestinal epithelial cells.

Review 6. The HMGB1-RAGE Inflammatory Pathway: Implications for Brain Injury-Induced Pulmonary Dysfunction.

7. Rpl30 and Hmgb1 are required for neurulation in golden hamster.

8. HMGB1 as an autocrine stimulus in human T98G glioblastoma cells: role in cell growth and migration.

Review 9. Neuroimmune basis of alcoholic brain damage.

Review 10. Role of HMGB1 in cardiovascular diseases.