Literature DB >> 14870861

Microwave synthesis solutions from Personal Chemistry.

Jon-Sverre Schanche1.   

Abstract

By fulfilling the specific design criteria required for safe and reproducible microwave synthesis, Personal Chemistry introduced the first microwave system designed for organic chemistry in 2000. The principle of microwave synthesis offers 3 major benefits to chemistry development: speed, reproducibility, and a scalable approach to compound synthesis. Additionally, significant advantages of our technical solution are ease of use, safety, verified synthesis methods to enable new users, and an efficient workflow that fits the drug discovery process. To gain the greatest advantages offered by microwave synthesis, Personal Chemistry has implemented a system called Coherent Synthesis. Incorporating planning systems, automation, distributed system access, searchable databases and reaction optimisation kits, the technology has already proved itself to dramatically improve the quality of output from medicinal chemistry for lead optimisation in all the major pharmaceutical and biotech companies.

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Year:  2003        PMID: 14870861     DOI: 10.1023/b:modi.0000006866.38392.f7

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  2 in total

Review 1.  Recent trends in microwave-assisted synthesis.

Authors:  Noel S Wilson; Gregory P Roth
Journal:  Curr Opin Drug Discov Devel       Date:  2002-07

2.  Automated library generation using sequential microwave-assisted chemistry. Application toward the Biginelli multicomponent condensation.

Authors:  A Stadler; C O Kappe
Journal:  J Comb Chem       Date:  2001 Nov-Dec
  2 in total
  6 in total

1.  Temperature measurements with two different IR sensors in a continuous-flow microwave heated system.

Authors:  Jonas Rydfjord; Fredrik Svensson; Magnus Fagrell; Jonas Sävmarker; Måns Thulin; Mats Larhed
Journal:  Beilstein J Org Chem       Date:  2013-10-10       Impact factor: 2.883

2.  Microwave-assisted Facile and Ultrafast Growth of ZnO Nanostructures and Proposition of Alternative Microwave-assisted Methods to Address Growth Stoppage.

Authors:  Abu Ul Hassan Sarwar Rana; Mingi Kang; Hyun-Seok Kim
Journal:  Sci Rep       Date:  2016-04-22       Impact factor: 4.379

3.  Rapid Nanoparticle Synthesis by Magnetic and Microwave Heating.

Authors:  Viktor Chikan; Emily J McLaurin
Journal:  Nanomaterials (Basel)       Date:  2016-05-05       Impact factor: 5.076

4.  Effect of Microwave Radiation Power on the Size of Aggregates of ZnO NPs Prepared Using Microwave Solvothermal Synthesis.

Authors:  Jacek Wojnarowicz; Tadeusz Chudoba; Stanisław Gierlotka; Witold Lojkowski
Journal:  Nanomaterials (Basel)       Date:  2018-05-18       Impact factor: 5.076

Review 5.  Continuous Flow Synthesis of Heterocycles: A Recent Update on the Flow Synthesis of Indoles.

Authors:  Marco Colella; Leonardo Degennaro; Renzo Luisi
Journal:  Molecules       Date:  2020-07-16       Impact factor: 4.411

6.  Ultrafast solid-liquid intercalation enabled by targeted microwave energy delivery.

Authors:  Ming-Jian Zhang; Yandong Duan; Chong Yin; Maofan Li; Hui Zhong; Eric Dooryhee; Kang Xu; Feng Pan; Feng Wang; Jianming Bai
Journal:  Sci Adv       Date:  2020-12-16       Impact factor: 14.136

  6 in total

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