Literature DB >> 1486854

Development of source testing, analytical, and mutagenicity bioassay procedures for evaluating emissions from municipal and hospital waste combustors.

R R Watts1, P M Lemieux, R A Grote, R W Lowans, R W Williams, L R Brooks, S H Warren, D M DeMarini, D A Bell, J Lewtas.   

Abstract

Incineration is currently being used for disposal of about 10% of the solid waste generated in the United States, and this percentage will likely increase as land disposal declines. Siting new incinerators, however, is often controversial because of concerns related to the possibility of adverse health effects and environmental contamination from long-term exposure to stack emissions. Specific concerns relate to the adequacies of a) stack emission testing protocols, b) existing regulations, and c) compliance monitoring and enforcement of regulations. U.S. Environmental Protection Agency laboratories are cooperatively conducting research aimed at developing new testing equipment and procedures that will allow a more comprehensive assessment of the complex mixture of organics that is present in stack emissions. These efforts are directed specifically toward developing source testing equipment and procedures, analytical procedures, and bioassay procedures. The objectives of this study were to field test two types of high-volume source dilution samplers, collect stack samples for use in developing analytical and mutagenicity bioassay procedures, and determine mutagenicity of organics associated with emission particles from two municipal waste combustors and a hospital waste combustor. Data are presented for particle concentrations and emission rates, extractable organic concentrations and emission rates, and Salmonella (Ames) mutagenic potency and emission rates. The mutagenic emission rates and emission factors are compared to other incinerators and combustion sources.

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Year:  1992        PMID: 1486854      PMCID: PMC1519628          DOI: 10.1289/ehp.9298227

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  8 in total

1.  DNA sequence analysis of revertants of the hisD3052 allele of Salmonella typhimurium TA98 using the polymerase chain reaction and direct sequencing: application to 1-nitropyrene-induced revertants.

Authors:  D A Bell; J G Levine; D M DeMarini
Journal:  Mutat Res       Date:  1991-02       Impact factor: 2.433

2.  Revised methods for the Salmonella mutagenicity test.

Authors:  D M Maron; B N Ames
Journal:  Mutat Res       Date:  1983-05       Impact factor: 2.433

3.  A simple modification of the Salmonella liquid-incubation assay. Increased sensitivity for detecting mutagens in human urine.

Authors:  N Y Kado; D Langley; E Eisenstadt
Journal:  Mutat Res       Date:  1983-07       Impact factor: 2.433

4.  Emissions of chlorinated organics from two municipal incinerators in Ontario.

Authors:  V Ozvacic; G Wong; H Tosine; R E Clement; J Osborne
Journal:  J Air Pollut Control Assoc       Date:  1985-08

5.  Mutagenicity assay of emission extracts from wood stoves: comparison with other emission parameters.

Authors:  G Löfroth; G Lazaridis; L Rudling
Journal:  Sci Total Environ       Date:  1986-12-31       Impact factor: 7.963

Review 6.  Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP.

Authors:  J Ashby; R W Tennant
Journal:  Mutat Res       Date:  1988-01       Impact factor: 2.433

Review 7.  Genotoxicity of complex mixtures: strategies for the identification and comparative assessment of airborne mutagens and carcinogens from combustion sources.

Authors:  J Lewtas
Journal:  Fundam Appl Toxicol       Date:  1988-05

8.  Polychlorinated dibenzo-p-dioxins and dibenzofurans in fly ash and cinders collected from several municipal incinerators in Japan.

Authors:  T Wakimoto; R Tatsukawa
Journal:  Environ Health Perspect       Date:  1985-02       Impact factor: 9.031

  8 in total
  8 in total

1.  Genotoxicity in cell lines induced by chronic exposure to water-soluble fullerenes using micronucleus test.

Authors:  Yasuharu Niwa; Naoharu Iwai
Journal:  Environ Health Prev Med       Date:  2006-11       Impact factor: 3.674

2.  Origin and health impacts of emissions of toxic by-products and fine particles from combustion and thermal treatment of hazardous wastes and materials.

Authors:  Stephania A Cormier; Slawo Lomnicki; Wayne Backes; Barry Dellinger
Journal:  Environ Health Perspect       Date:  2006-06       Impact factor: 9.031

Review 3.  Induction of mutation spectra by complex mixtures: approaches, problems, and possibilities.

Authors:  D M DeMarini
Journal:  Environ Health Perspect       Date:  1994-10       Impact factor: 9.031

Review 4.  Molecular analysis of mutations induced at the hisD3052 allele of Salmonella by single chemicals and complex mixtures.

Authors:  D M DeMarini; D A Bell; J G Levine; M L Shelton; A Abu-Shakra
Journal:  Environ Health Perspect       Date:  1993-10       Impact factor: 9.031

5.  Flavors of Fire: Assessing the Relative Toxicity of Smoke from Different Types of Wildfires.

Authors:  Nate Seltenrich
Journal:  Environ Health Perspect       Date:  2018-04-13       Impact factor: 9.031

6.  Chemistry, lung toxicity and mutagenicity of burn pit smoke-related particulate matter.

Authors:  Yong Ho Kim; Sarah H Warren; Ingeborg Kooter; Wanda C Williams; Ingrid J George; Samuel A Vance; Michael D Hays; Mark A Higuchi; Stephen H Gavett; David M DeMarini; Ilona Jaspers; M Ian Gilmour
Journal:  Part Fibre Toxicol       Date:  2021-12-16       Impact factor: 9.400

Review 7.  Mutagenicity and carcinogenicity of combustion emissions are impacted more by combustor technology than by fuel composition: A brief review.

Authors:  David M DeMarini; William P Linak
Journal:  Environ Mol Mutagen       Date:  2022-03-25       Impact factor: 3.579

8.  Mutagenicity and Lung Toxicity of Smoldering vs. Flaming Emissions from Various Biomass Fuels: Implications for Health Effects from Wildland Fires.

Authors:  Yong Ho Kim; Sarah H Warren; Q Todd Krantz; Charly King; Richard Jaskot; William T Preston; Barbara J George; Michael D Hays; Matthew S Landis; Mark Higuchi; David M DeMarini; M Ian Gilmour
Journal:  Environ Health Perspect       Date:  2018-01-24       Impact factor: 9.031

  8 in total

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