Literature DB >> 1486801

The gene for leukocyte antigen-related tyrosine phosphatase (LAR) is localized to human chromosome 1p32, a region frequently deleted in tumors of neuroectodermal origin.

F R Jirik1, K W Harder, I G Melhado, L L Anderson, A M Duncan.   

Abstract

In situ hybridization was employed to localize a cDNA probe from the human protein tyrosine phosphatase gene LAR to human metaphase chromosomes. LAR, a putative tumor suppressor gene, has been localized to 1p32, a chromosomal region that is frequently found deleted in human neuroblastoma and pheochromocytoma.

Entities:  

Mesh:

Substances:

Year:  1992        PMID: 1486801     DOI: 10.1159/000133418

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  2 in total

Review 1.  Receptor-like protein tyrosine phosphatases: alike and yet so different.

Authors:  R Schaapveld; B Wieringa; W Hendriks
Journal:  Mol Biol Rep       Date:  1997-11       Impact factor: 2.316

2.  LAR tyrosine phosphatase receptor: alternative splicing is preferential to the nervous system, coordinated with cell growth and generates novel isoforms containing extensive CAG repeats.

Authors:  J S Zhang; F M Longo
Journal:  J Cell Biol       Date:  1995-02       Impact factor: 10.539

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.