Literature DB >> 1482766

Dopamine transporter imaging with novel, selective cocaine analogs.

U Scheffel1, R F Dannals, D F Wong, F Yokoi, F I Carroll, M J Kuhar.   

Abstract

RTI-121 and RTI-122 are 3 beta-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [123I]RTI-121 and [123I]RTI-122 bind to dopamine transporters in vivo after intravenous administration and permit imaging of the transporters.

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Year:  1992        PMID： 1482766     DOI： 10.1097/00001756-199211000-00005

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  3 in total

Review 1.  Single-photon emission tomography imaging of dopamine terminal innervation: a potential clinical tool in Parkinson's disease.

Authors:  R B Innis
Journal:  Eur J Nucl Med       Date:  1994-01

2.  Comparison of [123I]beta-CIT and [123I]IPCIT as single-photon emission tomography radiotracers for the dopamine transporter in nonhuman primates.

Authors:  B E Scanley; M S al-Tikriti; M S Gandelman; M Laruelle; Y Zea-Ponce; R M Baldwin; S S Zoghbi; P B Hoffer; D S Charney; S Wang
Journal:  Eur J Nucl Med       Date:  1995-01

3.  Pharmacological characterization of a dopamine transporter ligand that functions as a cocaine antagonist.

Authors:  Rajeev I Desai; David K Grandy; Carl R Lupica; Jonathan L Katz
Journal:  J Pharmacol Exp Ther       Date:  2013-11-05       Impact factor: 4.030
  3 in total

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