Literature DB >> 1481610

[The preventive activity of monoclonal antibodies specific to the lipopolysaccharide of Francisella tularensis].

V S Khlebnikov, S S Vetchinin, G K Grechko, A A Averina, I R Golovlev, S F Averin, V E Zhemchugov, S I Konovalov, G A Anisimov, S S Afanas'ev.   

Abstract

The preventive activity of five monoclonal antibodies (McAb) in experimental tularemia was evaluated. McAb produced by hybridoma FB11-k (IgG2a), specific to F. tularensis lipopolysaccharide, prevented the death of mice and guinea pigs infected with F. tularensis virulent strain 503 of the holarctic subspecies.

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Year:  1992        PMID： 1481610

Source DB:  PubMed          Journal:  Zh Mikrobiol Epidemiol Immunobiol        ISSN： 0372-9311


  4 in total

1.  Structural analysis of a protective epitope of the Francisella tularensis O-polysaccharide.

Authors:  Michael J Rynkiewicz; Zhaohua Lu; Julia H Hui; Jacqueline Sharon; Barbara A Seaton
Journal:  Biochemistry       Date:  2012-07-02       Impact factor: 3.162

2.  Protective B-cell epitopes of Francisella tularensis O-polysaccharide in a mouse model of respiratory tularaemia.

Authors:  Zhaohua Lu; Guillermo Madico; Marly I Roche; Qi Wang; Julia H Hui; Hillary M Perkins; Joseph Zaia; Catherine E Costello; Jacqueline Sharon
Journal:  Immunology       Date:  2012-07       Impact factor: 7.397

3.  Generation and characterization of hybridoma antibodies for immunotherapy of tularemia.

Authors:  Zhaohua Lu; Marly I Roche; Julia H Hui; Berkay Unal; Philip L Felgner; Sunita Gulati; Guillermo Madico; Jacqueline Sharon
Journal:  Immunol Lett       Date:  2007-08-08       Impact factor: 3.685

4.  B-cell epitopes in GroEL of Francisella tularensis.

Authors:  Zhaohua Lu; Michael J Rynkiewicz; Guillermo Madico; Sheng Li; Chiou-Ying Yang; Hillary M Perkins; Seshi R Sompuram; Vani Kodela; Tong Liu; Timothy Morris; Daphne Wang; Marly I Roche; Barbara A Seaton; Jacqueline Sharon
Journal:  PLoS One       Date:  2014-06-26       Impact factor: 3.240
  4 in total

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