Literature DB >> 1481227

Steroid research at Syntex: "the pill" and cortisone.

C Djerassi1.   

Abstract

The period from late 1949 through 1951 was an extraordinarily productive one in steroid chemistry and especially so at Syntex S.A. in Mexico City. Two of the most important Syntex contributions--the synthesis of 19-nor-17 alpha-ethynyltestosterone (norethindrone) and of cortisone from diosgenin--are described from a historical perspective.

Entities:  

Keywords:  Adrenal Cortex Hormones; Americas; Biology; Contraception; Contraception Research; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods; Developed Countries; Developing Countries; Economic Factors; Endocrine System; Family Planning; Historical Survey; Hormones; Industry; Ingredients And Chemicals; Latin America; Litigation; Macroeconomic Factors; Mexico; Norethindrone; Norethynodrel; North America; Northern America; Oral Contraceptives; Physiology; United States; Wisconsin

Mesh:

Substances:

Year:  1992        PMID: 1481227     DOI: 10.1016/0039-128x(92)90016-3

Source DB:  PubMed          Journal:  Steroids        ISSN: 0039-128X            Impact factor:   2.668


  9 in total

1.  Effects of estrogen-like plant compounds on the vaginal epithelium pituitary, adrenal glands, and uterus of rats.

Authors:  Gismar Mc Rodrigues; Bruno Db Borges; Leticia Gabriela Q Moreira; Érica Aparecida G Rossete; Suzelei de Castro Franca
Journal:  Exp Biol Med (Maywood)       Date:  2018-12-03

2.  Strategies for dereplication of natural compounds using high-resolution tandem mass spectrometry.

Authors:  Tobias Kind; Oliver Fiehn
Journal:  Phytochem Lett       Date:  2016-11-17       Impact factor: 1.679

3.  Scalable synthesis of cortistatin A and related structures.

Authors:  Jun Shi; Georg Manolikakes; Chien-Hung Yeh; Carlos A Guerrero; Ryan A Shenvi; Hiroki Shigehisa; Phil S Baran
Journal:  J Am Chem Soc       Date:  2011-05-03       Impact factor: 15.419

4.  Diarylheptanoids from Dioscorea villosa (Wild Yam).

Authors:  Shi-Hui Dong; Dejan Nikolić; Charlotte Simmler; Feng Qiu; Richard B van Breemen; Djaja D Soejarto; Guido F Pauli; Shao-Nong Chen
Journal:  J Nat Prod       Date:  2012-12-17       Impact factor: 4.050

5.  From an ent-Estrane, through a nat-Androstane, to the Total Synthesis of the Marine-Derived Δ8,9-Pregnene (+)-03219A.

Authors:  Zachary A Shalit; Lucas C Valdes; Wan Shin Kim; Glenn C Micalizio
Journal:  Org Lett       Date:  2021-02-26       Impact factor: 6.005

Review 6.  Antiandrogenic and antimineralocorticoid health benefits of COC containing newer progestogens: dienogest and drospirenone.

Authors:  Pedro-Antonio Regidor; Adolf E Schindler
Journal:  Oncotarget       Date:  2017-08-03

7.  Diosgenin hemihydrate.

Authors:  María-Guadalupe Hernández Linares; Sylvain Bernès; Marcos Flores-Alamo; Gabriel Guerrero-Luna; Anselmo A Martínez-Gallegos
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-07-07

8.  Potential compound from herbal food of Rhizoma Polygonati for treatment of COVID-19 analyzed by network pharmacology: Viral and cancer signaling mechanisms.

Authors:  Chenglin Mu; Yifan Sheng; Qian Wang; Amr Amin; Xugang Li; Yingqiu Xie
Journal:  J Funct Foods       Date:  2020-08-14       Impact factor: 4.451

Review 9.  The clinical relevance of progestogens in hormonal contraception: Present status and future developments.

Authors:  Pedro-Antonio Regidor
Journal:  Oncotarget       Date:  2018-10-02
  9 in total

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