Literature DB >> 14806401

Acquired resistance to 'Melarsen', tryparsamide and amidines in pathogenic trypanosomes after treatment with 'Melarsen' alone.

I M ROLLO, J WILLIAMSON.   

Abstract

Entities:  

Keywords:  AMIDINES; TRYPANOSOMA; TRYPARSAMIDE

Mesh：

Substances：

Year:  1951        PMID： 14806401     DOI： 10.1038/167147a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  15 in total

1.  Drug resistance in trapanososmes: cross-resitance analyses.

Authors:  J WILLIAMSON; I M ROLLO
Journal:  Br J Pharmacol Chemother       Date:  1959-12

2.  Trypanosomiasis in Africa.

Authors: 
Journal:  Br Med J       Date:  1956-12-15

3.  Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.

Authors:  Enock Matovu; Mhairi L Stewart; Federico Geiser; Reto Brun; Pascal Mäser; Lynsey J M Wallace; Richard J Burchmore; John C K Enyaru; Michael P Barrett; Ronald Kaminsky; Thomas Seebeck; Harry P de Koning
Journal:  Eukaryot Cell       Date:  2003-10

4.  Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes.

Authors:  Nicola Baker; Lucy Glover; Jane C Munday; David Aguinaga Andrés; Michael P Barrett; Harry P de Koning; David Horn
Journal:  Proc Natl Acad Sci U S A       Date:  2012-06-18       Impact factor: 11.205

Review 5.  Antiparasitic chemotherapy: from genomes to mechanisms.

Authors:  David Horn; Manoj T Duraisingh
Journal:  Annu Rev Pharmacol Toxicol       Date:  2013-09-11       Impact factor: 13.820

6.  An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei.

Authors:  Juan P de Macêdo; Gabriela Schumann Burkard; Moritz Niemann; Michael P Barrett; Henri Vial; Pascal Mäser; Isabel Roditi; André Schneider; Peter Bütikofer
Journal:  PLoS Pathog       Date:  2015-05-06       Impact factor: 6.823

Review 7.  Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story.

Authors:  Nicola Baker; Harry P de Koning; Pascal Mäser; David Horn
Journal:  Trends Parasitol       Date:  2013-01-30

8.  Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei.

Authors:  Ali H Alghamdi; Jane C Munday; Gustavo Daniel Campagnaro; Dominik Gurvic; Fredrik Svensson; Chinyere E Okpara; Arvind Kumar; Juan Quintana; Maria Esther Martin Abril; Patrik Milić; Laura Watson; Daniel Paape; Luca Settimo; Anna Dimitriou; Joanna Wielinska; Graeme Smart; Laura F Anderson; Christopher M Woodley; Siu Pui Ying Kelly; Hasan Ms Ibrahim; Fabian Hulpia; Mohammed I Al-Salabi; Anthonius A Eze; Teresa Sprenger; Ibrahim A Teka; Simon Gudin; Simone Weyand; Mark Field; Christophe Dardonville; Richard R Tidwell; Mark Carrington; Paul O'Neill; David W Boykin; Ulrich Zachariae; Harry P De Koning
Journal:  Elife       Date:  2020-08-11       Impact factor: 8.140

9.  Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol.

Authors:  Fabrice E Graf; Philipp Ludin; Tanja Wenzler; Marcel Kaiser; Reto Brun; Patient Pati Pyana; Philippe Büscher; Harry P de Koning; David Horn; Pascal Mäser
Journal:  PLoS Negl Trop Dis       Date:  2013-10-10

10.  Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs.

Authors:  Jane C Munday; Anthonius A Eze; Nicola Baker; Lucy Glover; Caroline Clucas; David Aguinaga Andrés; Manal J Natto; Ibrahim A Teka; Jennifer McDonald; Rebecca S Lee; Fabrice E Graf; Philipp Ludin; Richard J S Burchmore; C Michael R Turner; Andy Tait; Annette MacLeod; Pascal Mäser; Michael P Barrett; David Horn; Harry P De Koning
Journal:  J Antimicrob Chemother       Date:  2013-11-13       Impact factor: 5.790
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