Literature DB >> 14804

Enzyme activities in human liver biopsies: assay methods and activities of some lysosomal and membrane-bound enzymes in control tissue and serum.

C A Seymour, T J Peters.   

Abstract

1. Highly sensitive technique are described for the assay of plasma membrane (5'-nucleotidase, alkaline phosphatase), microsomal (neutral alpha-glucosidase, leucyl-2-naphthylamidase) and biliary canalicular (gamma-glutamyltransferase) enzymes and for nine acid hydrolases (acid phosphatase, phosphodiesterase, beta-glucosidase, alpha-glucosidase, alpha-galactosidase, beta-galactosidase, alpha-mannosidase, N-acetyl-beta-glucosaminidase, beta-glucuronidase) in human liver. 2. Optimum and specific assay systems have been developed which give linear kinetics for all enzymes. 3. The range of enzyme activities in samples of human liver, obtained by closed needle biopsy, and sera have been determined.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 14804     DOI： 10.1042/cs0520229

Source DB:  PubMed          Journal:  Clin Sci Mol Med        ISSN： 0301-0538


  16 in total

1.  Gamma-glutamyltransferase levels in ascitic fluid and liver from patients with primary hepatoma.

Authors:  T J Peters; C A Seymour; G Wells; F Fakunle; G Neale
Journal:  Br Med J       Date:  1977-06-18

2.  Does iron affect osteoblast function? Studies in vitro and in patients with chronic liver disease.

Authors:  T Diamond; R Pojer; D Stiel; A Alfrey; S Posen
Journal:  Calcif Tissue Int       Date:  1991-06       Impact factor: 4.333

3.  Enhancement of ileal adaptation by prednisolone after proximal small bowel resection in the rat.

Authors:  J Scott; R M Batt; T J Peters
Journal:  Gut       Date:  1979-10       Impact factor: 23.059

4.  Analytical subcellular fractionation of needle-biopsy specimens from human liver.

Authors:  T J Peters; C A Seymour
Journal:  Biochem J       Date:  1978-08-15       Impact factor: 3.857

5.  Studies on the kinetic properties and subcellular localization of adenine nucleotide phosphatases in peripheral blood lymphocytes from control subjects and patients with common variable primary hypogammaglobulinaemia.

Authors:  G P Smith; T Shah; A D Webster; T J Peters
Journal:  Clin Exp Immunol       Date:  1982-08       Impact factor: 4.330

6.  The possible role of lysosomal enzymes in the pathogenesis of hypertensive cerebral lesions in spontaneously hypertensive rats.

Authors:  C H Chue; N Yukioka; E Yamada; F Hazama
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

7.  Enzymic oxidation of unconjugated bilirubin by rat liver.

Authors:  R Cardenas-Vazquez; O Yokosuka; B H Billing
Journal:  Biochem J       Date:  1986-06-15       Impact factor: 3.857

8.  Electron microscopic cytochemical localization of nucleoside phosphatases in normal and chronic granulocytic leukaemic human neutrophils.

Authors:  P D Wilson; G J Rustin; G P Smith; T J Peters
Journal:  Histochem J       Date:  1981-01

9.  Glucagon-stimulable adenylyl cyclase in rat liver. The impact of streptozotocin-induced diabetes mellitus.

Authors:  R R Dighe; F J Rojas; L Birnbaumer; A J Garber
Journal:  J Clin Invest       Date:  1984-04       Impact factor: 14.808

10.  The mechanism of hepatic iron uptake from native and denatured transferrin and its subcellular metabolism in the liver cell.

Authors:  J P Milsom; R G Batey
Journal:  Biochem J       Date:  1979-07-15       Impact factor: 3.857
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.