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Literature DB >> 14803630

The effect of cortisone and adrenocorticotrophic hormone on the concentration of circulating antibody.

Abstract

The administration of adrenocorticotrophic hormone and of cortisone was found to result in a reduction in the concentration of antipneumococcal antibody in the circulation of rabbits. This reduction occurred both when the hormones were administered at the beginning of immunization and after immunization was well advanced. Marked atrophic changes in lymphoid tissue and a diminution in the number of various types of mononuclear cells followed upon the hormone administration. The possible bearing of these observations on theories concerning the sites of antibody production is discussed.

Entities: Chemical Disease Species

Keywords: ACTH; ANTIGENS AND ANTIBODIES; CORTISONE

Mesh：

Substances：

Year: 1951 PMID： 14803630 PMCID： PMC2136054 DOI： 10.1084/jem.93.1.37

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

10 in total

21 in total

1. Effect of cortisone in experimental syphilis in rabbits.

Authors: H SCHMIDT; L DORPH-PETERSEN; M W BENTZON
Journal: Br J Vener Dis Date: 1957-12

2. Effect of cortisone on the defence mechanisms of the body.

Authors: D L BILBEY; T NICOL; R S SNELL
Journal: Br Med J Date: 1956-10-06

3. A species difference with regard to the effect of cortisone acetate on body weight, gamma-globulin and circulating antitoxin levels.

Authors: D A LONG; J SHEWELL
Journal: J Hyg (Lond) Date: 1956-12

8. Quantitative antibody studies in man. I. The effect of adrenal insufficiency and of cortisone on the level of circulating antibodies.

Authors: D L LARSON; L J TOMLINSON
Journal: J Clin Invest Date: 1951-12 Impact factor: 14.808

9. The influence of ACTH on the sensitizing and immunizing antibodies of inhalant allergy.

Authors: M H LOVELESS
Journal: Bull N Y Acad Med Date: 1951-08

10. The histology of antigenically stimulated lymph nodes in rabbits given ACTH or cortisone.

Authors: J M CRAIG
Journal: Am J Pathol Date: 1952 Jul-Aug Impact factor: 4.307

The effect of cortisone and adrenocorticotrophic hormone on the concentration of circulating antibody.

1. Physicochemical studies on lymph and lymphocyte extracts from normal and stimulated lymphatic tissue.

2. The effect of adrenocorticotrophic hormone and X-ray on the amount of circulating antibody.

3. Effect of adrenocorticotrophic hormone on rheumatoid arthritis.

4. The role of allergy in the pathogenesis of rheumatic fever.

5. THE OCCURRENCE OF NORMAL SERUM GAMMA-GLOBULIN IN HUMAN LYMPHOCYTES.

6. Electrophoretic and chemical characterization of human lymphoid tissue and calf thymus.

7. THE FORMATION OF AGGLUTININS WITHIN LYMPH NODES.

8. CELLULAR REACTIONS TO A DYE-PROTEIN WITH A CONCEPT OF THE MECHANISM OF ANTIBODY FORMATION.

9. CHEMICAL STUDIES ON BACTERIAL AGGLUTINATION : I. A METHOD.

10. IMPAIRMENT OF ANTIBODY RESPONSE IN PYRIDOXINE-DEFICIENT RATS.

1. Effect of cortisone in experimental syphilis in rabbits.

2. Effect of cortisone on the defence mechanisms of the body.

3. A species difference with regard to the effect of cortisone acetate on body weight, gamma-globulin and circulating antitoxin levels.

4. Studies on cortisone and antibiotics for prompt therapeutic control of typhoid fever and scrub typhus.

5. Typhoid osteomyelitis of spine treated with chloramphenicol.

6. Use of ACTH and cortisone in surgery.

7. Influence of Cortisone on the C'4 Titer in Guinea Pigs.

8. Quantitative antibody studies in man. I. The effect of adrenal insufficiency and of cortisone on the level of circulating antibodies.

9. The influence of ACTH on the sensitizing and immunizing antibodies of inhalant allergy.

10. The histology of antigenically stimulated lymph nodes in rabbits given ACTH or cortisone.