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Literature DB >> 1479383

Antifungal activity of meridine, a natural product from the marine sponge Corticium sp.

P J McCarthy¹, T P Pitts, G P Gunawardana, M Kelly-Borges, S A Pomponi.

Abstract

Meridine [1], a polycyclic alkaloid derived from the marine sponge Corticium sp., was found to inhibit the growth of Candida albicans and Cryptococcus neoformans. Activity was also observed against Trichophyton mentagrophytes and Epidermophyton floccosum. Studies of the mechanism of action of this agent have shown an inhibition of nucleic acid biosynthesis.

Entities: Chemical Species

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Year: 1992 PMID： 1479383 DOI： 10.1021/np50089a016

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

15 in total

1. REGIOSELECTIVE MULTICOMPONENT DOMINO REACTIONS PROVIDING RAPID AND EFFICIENT ROUTES TO FUSED ACRIDINES.

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Journal: Heterocycles Date: 2013-12-17 Impact factor: 0.831

2. Efficacy of alkaloid (-)-corypalmine against spore germination of some fungi.

Authors: S Maurya; J S Srivastava; R N Jha; V B Pandey; U P Singh
Journal: Folia Microbiol (Praha) Date: 2002 Impact factor: 2.099

3. Toward the Total Synthesis of Alpkinidine: Synthesis of Haloquinone CE Ring System Synthons and Attempted Nucleophilic Bisannulation.

Authors: Marco Buccini; Louisa Tham; Francis Dhoro; Brian W Skelton; Craig M Williams; Matthew J Piggott
Journal: ACS Omega Date: 2022-06-01

4. Two plant alkaloids isolated from Corydalis longipes as potential antifungal agents.

Authors: N V Singh; S Azmi; S Maurya; U P Singh; R N Jha; V B Pandey
Journal: Folia Microbiol (Praha) Date: 2003 Impact factor: 2.099

5. Individual and combined effect of (+/-)-alpha-hydrastine and (+/-)-beta-hydrastine on spore germination of some fungi.

Authors: M Goel; U P Singh; R N Jha; V B Pandey; M B Pandey
Journal: Folia Microbiol (Praha) Date: 2003 Impact factor: 2.099

Antifungal activity of meridine, a natural product from the marine sponge Corticium sp.

1. REGIOSELECTIVE MULTICOMPONENT DOMINO REACTIONS PROVIDING RAPID AND EFFICIENT ROUTES TO FUSED ACRIDINES.

2. Efficacy of alkaloid (-)-corypalmine against spore germination of some fungi.

3. Toward the Total Synthesis of Alpkinidine: Synthesis of Haloquinone CE Ring System Synthons and Attempted Nucleophilic Bisannulation.

4. Two plant alkaloids isolated from Corydalis longipes as potential antifungal agents.

5. Individual and combined effect of (+/-)-alpha-hydrastine and (+/-)-beta-hydrastine on spore germination of some fungi.

6. Halogenated cyclic peptides isolated from the sponge Corticium sp.

7. Effect of berberine and (+/-)-bicuculline isolated from Corydalis chaerophylla on spore germination of some fungi.

8. In vitro anti-inflammatory and pro-aggregative effects of a lipid compound, petrocortyne A, from marine sponges.

9. Evaluation of pyridoacridine alkaloids in a zebrafish phenotypic assay.

10. Antifungal Activity of Nor-securinine Against Some Phytopathogenic Fungi.