| Literature DB >> 1477963 |
Abstract
Female rats were injected with testosterone propionate on the 1st and 3rd days of life. In addition, some females received 200 micrograms of the anti-androgen, hydroxyflutamide. Females receiving anti-androgen directly to the perineum, including the muscles bulbocavernosus and levator ani, had fewer surviving spinal nucleus of the bulbocavernosus (SNB) motoneurons than did females receiving the anti-androgen systemically. These results indicate that androgen acts upon the target muscles to spare developing SNB motoneurons from death.Entities:
Mesh：
Substances：
Year: 1992 PMID： 1477963 DOI： 10.1016/0165-3806(92)90208-e
Source DB: PubMed Journal: Brain Res Dev Brain Res ISSN： 0165-3806