Literature DB >> 14770348

[Early course of illness in first episode schizophrenia with long duration of untreated illness - a comparative study].

D Köhn1, Antje Niedersteberg, Anke Wieneke, A Bechdolf, R Pukrop, S Ruhrmann, Frauke Schultze-Lutter, W Maier, J Klosterkötter.   

Abstract

When a long duration of untreated illness (DUI) is correlated with an unfavourable progression of schizophrenia in the same way as that of a long duration of untreated psychosis (DUP), the characteristics of patients with a long DUI are of particular interest for early recognition and early intervention programmes. With this background, demographic data and early symptoms were collected from 82 first time in-patients with schizophrenia using the IRAOS (Interview for the Retrospective Assessment of the Onset of Schizophrenia). In the total sample, the average DUI was almost 5.9 years. On the basis of the DUI median (5.2 yrs), the random sample was divided into two groups: one with long (n = 41) and one with short (n = 41) DUI. When comparing both groups in terms of socio-demographic data, no significant differences could be found (with the exception of age at first admission: 28 - 32 yrs). On a psychopathological level, patients with long DUI were prone to depressive moods, anxiety, compulsive symptoms and showed early signs of disturbances in bodily perception. An educational campaign should sensitize both employees working in primary care and experts who diagnose and treat psychological illnesses, to the fact that these symptoms could point to a prodrome even when the patient has passed the typical age of being at risk from schizophrenia.

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Year:  2004        PMID: 14770348     DOI: 10.1055/s-2003-812509

Source DB:  PubMed          Journal:  Fortschr Neurol Psychiatr        ISSN: 0720-4299            Impact factor:   0.752


  6 in total

1.  Recent approaches to psychological interventions for people at risk of psychosis.

Authors:  Andreas Bechdolf; Lisa J Phillips; Shona M Francey; Steven Leicester; Anthony P Morrison; Verena Veith; Joachim Klosterkötter; Patrick D McGorry
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2006-04       Impact factor: 5.270

Review 2.  [Early recognition and intervention for schizophrenia].

Authors:  N Mossaheb; G Wiesegger; G P Amminger; S Kasper; J Tauscher
Journal:  Nervenarzt       Date:  2006-01       Impact factor: 1.214

3.  Frequency and pattern of childhood symptom onset reported by first episode schizophrenia and clinical high risk youth.

Authors:  Kristen A Woodberry; Rachael A Serur; Sean B Hallinan; Raquelle I Mesholam-Gately; Anthony J Giuliano; Joanne D Wojcik; Matcheri S Keshavan; Jean A Frazier; Jill M Goldstein; Martha E Shenton; Robert W McCarley; Larry J Seidman
Journal:  Schizophr Res       Date:  2014-06-10       Impact factor: 4.939

4.  Early detection of schizophrenia: current evidence and future perspectives.

Authors:  Heinz Häfner; Kurt Maurer
Journal:  World Psychiatry       Date:  2006-10       Impact factor: 49.548

5.  Duration of unspecific prodromal and clinical high risk states, and early help-seeking in first-admission psychosis patients.

Authors:  Frauke Schultze-Lutter; Jonas Rahman; Stephan Ruhrmann; Chantal Michel; Benno G Schimmelmann; Wolfgang Maier; Joachim Klosterkötter
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2015-07-09       Impact factor: 4.328

6.  Evidence for separate diseases?: Stages of one disease or different combinations of symptom dimensions?

Authors:  Heinz Häfner; Wolfram an der Heiden; Kurt Maurer
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2008-06       Impact factor: 5.270

  6 in total

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