Literature DB >> 14770095

Musculoskeletal aging.

Suzanne G Leveille1.   

Abstract

PURPOSE OF REVIEW: Chronic conditions associated with musculoskeletal aging contribute to a heavy functional and economic burden for our rapidly aging population. The purpose of this article is to review recent investigations in musculoskeletal epidemiology related to aging. RECENT
FINDINGS: Well over half the older adults in the United States report chronic joint symptoms. With the projected growth of the older population in the next 25 years, the number of elders with arthritis is expected to double to 41 million. Accumulating evidence points to large ethnic and racial differences in the prevalence of arthritis. Primary care interventions to improve self-management of arthritis have been developed and tested, although further work in this area is warranted. Progress is being made in other major chronic conditions associated with aging. Research shows that optimal screening for osteoporotic fracture risk will require risk factor information in addition to bone densitometry. Recent findings shed new light on treatments for osteoporosis and musculoskeletal pain. A new field of study is investigating sarcopenia, or skeletal muscle loss, in very old populations. Research to date has uncovered evidence that this disabling condition may be the result of immunologic and hormonal changes related to aging.
SUMMARY: Investigations in many areas are contributing to a better understanding of the major chronic conditions that affect the lives of many older adults. However, the surge in the elderly population will require far greater research and intervention efforts to postpone or prevent a huge population burden of disability related to common musculoskeletal problems of old age.

Entities:  

Mesh:

Year:  2004        PMID: 14770095     DOI: 10.1097/00002281-200403000-00007

Source DB:  PubMed          Journal:  Curr Opin Rheumatol        ISSN: 1040-8711            Impact factor:   5.006


  26 in total

1.  Middle-aged and mobility-limited: prevalence of disability and symptom attributions in a national survey.

Authors:  Elizabeth A Gardener; Felicia A Huppert; Jack M Guralnik; David Melzer
Journal:  J Gen Intern Med       Date:  2006-10       Impact factor: 5.128

2.  A painful interface between normal aging and disease.

Authors:  Shari Miura Ling; Eleanor M Simonsick; Luigi Ferrucci
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2007-06       Impact factor: 6.053

3.  Fourier transform infrared imaging and MR microscopy studies detect compositional and structural changes in cartilage in a rabbit model of osteoarthritis.

Authors:  Xiaohong Bi; Xu Yang; Mathias P G Bostrom; Dorota Bartusik; Sharan Ramaswamy; Kenneth W Fishbein; Richard G Spencer; Nancy Pleshko Camacho
Journal:  Anal Bioanal Chem       Date:  2006-12-02       Impact factor: 4.142

4.  Associations between inflammatory markers, candidate polymorphisms and physical performance in older Danish twins.

Authors:  Kristina Tiainen; Mikael Thinggaard; Marja Jylhä; Else Bladbjerg; Kaare Christensen; Lene Christiansen
Journal:  Exp Gerontol       Date:  2011-11-12       Impact factor: 4.032

5.  Gender-specific pleiotropic bone-muscle relationship in the elderly from a nationwide survey (KNHANES IV).

Authors:  J H Huh; M K Song; K H Park; K J Kim; J E Kim; Y M Rhee; S-K Lim
Journal:  Osteoporos Int       Date:  2013-10-23       Impact factor: 4.507

Review 6.  Role of MicroRNA-141 in the Aging Musculoskeletal System: A Current Overview.

Authors:  Babatunde Fariyike; Quante Singleton; Monte Hunter; William D Hill; Carlos M Isales; Mark W Hamrick; Sadanand Fulzele
Journal:  Mech Ageing Dev       Date:  2018-12-07       Impact factor: 5.432

Review 7.  Pain management today - what have we learned?

Authors:  Richard M Langford
Journal:  Clin Rheumatol       Date:  2006-06-02       Impact factor: 2.980

8.  Age and race effects on pain sensitivity and modulation among middle-aged and older adults.

Authors:  Joseph L Riley; Yenisel Cruz-Almeida; Toni L Glover; Christopher D King; Burel R Goodin; Kimberly T Sibille; Emily J Bartley; Matthew S Herbert; Adriana Sotolongo; Barri J Fessler; David T Redden; Roland Staud; Laurence A Bradley; Roger B Fillingim
Journal:  J Pain       Date:  2013-11-14       Impact factor: 5.820

9.  [Prevalence of musculoskeletal complaints and self-reported joint osteoarthritis in the population of Herne : a telephone survey].

Authors:  U Thiem; J Schumacher; J Zacher; G-R Burmester; L Pientka
Journal:  Z Rheumatol       Date:  2008-09       Impact factor: 1.372

Review 10.  Sarcopenia and Menopause: The Role of Estradiol.

Authors:  Annalisa Geraci; Riccardo Calvani; Evelyn Ferri; Emanuele Marzetti; Beatrice Arosio; Matteo Cesari
Journal:  Front Endocrinol (Lausanne)       Date:  2021-05-19       Impact factor: 5.555

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