Literature DB >> 14769100

Effect of methylphenidate on time perception in children with attention-deficit/hyperactivity disorder.

Ronald L Baldwin1, John J Chelonis, Rebecca A Flake, Mark C Edwards, Charles R Feild, Julie B Meaux, Merle G Paule.   

Abstract

The effects of methylphenidate (MPH) on performance of a time-production task were studied in 17 children with attention-deficit/hyperactivity disorder who participated in 1 test session on and 1 off MPH. Participants held a response lever down for at least 10 but no longer than 14 s. Administration of MPH had no effect on the number of correct responses or on the mean duration of lever holds. MPH administration significantly decreased timing response variability, increased holds of 10- to 11-s duration, and decreased lever holds of extremely short durations. These results indicate that administration of MPH resulted in more precise timing performance without changing the mean duration of lever holds, suggesting an enhancement in working memory.

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Year:  2004        PMID： 14769100     DOI： 10.1037/1064-1297.12.1.57

Source DB:  PubMed          Journal:  Exp Clin Psychopharmacol        ISSN： 1064-1297            Impact factor:   3.157


  15 in total

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Review 3.  Cognitive and behavioral training interventions to promote self-control.

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5.  Neurodevelopment of children exposed to anesthesia: design of the Mayo Anesthesia Safety in Kids (MASK) study.

Authors:  Stephen J Gleich; Randall Flick; Danqing Hu; Michael J Zaccariello; Robert C Colligan; Slavica K Katusic; Darrell R Schroeder; Andrew Hanson; Shonie Buenvenida; Robert T Wilder; Juraj Sprung; Robert G Voigt; Merle G Paule; John J Chelonis; David O Warner
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6.  Impulsiveness as a timing disturbance: neurocognitive abnormalities in attention-deficit hyperactivity disorder during temporal processes and normalization with methylphenidate.

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8.  A time-based intervention to treat impulsivity in male and female rats.

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9.  The effects of methylphenidate on cerebral activations to salient stimuli in healthy adults.

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10.  An evaluation of the effect of methylphenidate on working memory, time perception, and choice impulsivity in children with ADHD.

Authors:  Mileini Campez; Joseph S Raiker; Kelcey Little; Amy R Altszuler; Brittany M Merrill; Fiona L Macphee; Elizabeth M Gnagy; Andrew R Greiner; Erica D Musser; Erika K Coles; William E Pelham
Journal:  Exp Clin Psychopharmacol       Date:  2021-01-21       Impact factor: 3.157
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