Literature DB >> 14766251

Vacuum-assisted closure in the treatment of gynecologic oncology wound failures.

Veronica L Schimp1, Cynthia Worley, Sandi Brunello, Charles C Levenback, Judith K Wolf, Charlotte C Sun, Diane C Bodurka, Pedro T Ramirez.   

Abstract

OBJECTIVE: Negative pressure wound vacuum therapy can expedite the healing of complex wound failures. Our aim was to evaluate the use of a vacuum-assisted closure (VAC) device to treat complex wound failures in gynecologic oncology patients.
METHODS: We retrospectively identified 27 patients with gynecologic malignancies in whom the device was used to treat complex wound failures from January 2001 to May 2002 at our institution. We analyzed operative data and information regarding the diagnosis and management of these complex wound failures and the length of time the device was used.
RESULTS: The procedures performed before wound VAC placement were total abdominal hysterectomy with bilateral salpingo-oopherectomy with or without tumor reductive surgery in 14 patients, vulvectomy with or without inguinal lymph node dissection in five patients, skin or myocutaneous grafting in three patients, parastomal herniorrhaphy in two patients, retroperitoneal lymph node dissection in two patients, and incision and drainage of a gluteal abscess after radiation therapy in one patient. Four of the 27 patients had the VAC device placed at the time of a reoperation, while the remaining 23 patients had the VAC device placed postoperatively for wound failures. Wound breakdown occurred at a median of 9 days (range: 0-88 days) postoperatively. Overall, there was a 96% reduction (range: 0-100%) in the median size of wound defects from 330 to 14.0 cm(3) with use of the VAC device. The median number of days of VAC therapy was 32 days (range: 3-88 days). Twenty patients used this device as outpatients, and the charge per day was approximately US$150.00. One patient experienced bleeding, and 26 patients experienced no complications. The only complaint was pain during dressing changes (67% of patients). The mean follow-up was 52 days (range: 0-270 days). At the time of last contact, 26 (96%) of 27 patients had complete wound healing.
CONCLUSIONS: VAC therapy is a novel treatment using controlled negative pressure to evacuate wound fluid, stimulate granulation tissue, and to decrease bacterial colonization of the wound. Our experience indicates that this is a safe method to treat complex wound failures in gynecologic oncology patients.

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Year:  2004        PMID: 14766251     DOI: 10.1016/j.ygyno.2003.10.055

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  10 in total

Review 1.  Radiotherapy and wound healing.

Authors:  Emma-Louise Dormand; Paul E Banwell; Timothy E E Goodacre
Journal:  Int Wound J       Date:  2005-06       Impact factor: 3.315

Review 2.  Pain and trauma in negative pressure wound therapy: a review.

Authors:  Dominic Upton; Abbye Andrews
Journal:  Int Wound J       Date:  2013-03-12       Impact factor: 3.315

Review 3.  Retained Negative Pressure Wound Therapy Foams as a Cause of Infection Persistence.

Authors:  Konstantinos Anagnostakos; Andreas Thiery; Ismail Sahan
Journal:  Adv Wound Care (New Rochelle)       Date:  2020-09-10       Impact factor: 4.730

Review 4.  Growth factors, silver dressings and negative pressure wound therapy in the management of hard-to-heal postoperative wounds in obstetrics and gynecology: a review.

Authors:  Paweł Jan Stanirowski; Anna Wnuk; Krzysztof Cendrowski; Włodzimierz Sawicki
Journal:  Arch Gynecol Obstet       Date:  2015-04-12       Impact factor: 2.344

5.  Vacuum-assisted closure of necrotic and infected cranial wound with loss of dura mater: A technical note.

Authors:  Osama Ahmed; Christopher M Storey; Shihao Zhang; Marjorie R Chelly; Melvin S Yeoh; Anil Nanda
Journal:  Surg Neurol Int       Date:  2015-01-22

6.  The Management of Vacuum-assisted Closure Following Vulvectomy with Skin Grafting.

Authors:  Jun Hu; Hope K Haefner
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-04-26

7.  Chinese Trauma Surgeon Association for management guidelines of vacuum sealing drainage application in abdominal surgeries-Update and systematic review.

Authors:  Yang Li; Pei-Yuan Li; Shi-Jing Sun; Yuan-Zhang Yao; Zhan-Fei Li; Tao Liu; Fan Yang; Lian-Yang Zhang; Xiang-Jun Bai; Jing-Shan Huo; Wu-Bing He; Jun Ouyang; Lei Peng; Ping Hu; Yan-An Zhu; Ping Jin; Qi-Feng Shao; Yan-Feng Wang; Rui-Wu Dai; Pei-Yang Hu; Hai-Ming Chen; Ge-Fei Wang; Yong-Gao Wang; Hong-Xu Jin; Chang-Ju Zhu; Qi-Yong Zhang; Biao Shao; Xi-Guang Sang; Chang-Lin Yin
Journal:  Chin J Traumatol       Date:  2019-02-14

8.  Secondary healing strategy for difficult wound closure in invasive vulvar cancer: a pilot case-control study.

Authors:  Altamiro Ribeiro Dias-Jr; José Maria Soares-Jr; Maria Beatriz Sartor de Faria; Maria Luiza Noqueira Dias Genta; Jesus Paula Carvalho; Edmund C Baracat
Journal:  Clinics (Sao Paulo)       Date:  2019-09-02       Impact factor: 2.365

9.  Outcomes of skin graft reconstructions with the use of Vacuum Assisted Closure (VAC(R)) dressing for irradiated extremity sarcoma defects.

Authors:  Alex Senchenkov; Paul M Petty; James Knoetgen; Steven L Moran; Craig H Johnson; Ricky P Clay
Journal:  World J Surg Oncol       Date:  2007-11-29       Impact factor: 2.754

10.  Silver negative pressure dressing with vacuum-assisted closure of massive pelvic and extremity wounds.

Authors:  Herrick J Siegel; Diego F Herrera; Jason Gay
Journal:  Clin Orthop Relat Res       Date:  2014-03       Impact factor: 4.176

  10 in total

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