Literature DB >> 14765718

Development of the University of Wisconsin donation After Cardiac Death Evaluation Tool.

Jonathan Lewis1, James Peltier, Helen Nelson, William Snyder, Kristi Schneider, Dina Steinberger, Michael Anderson, Alexander Krichevsky, James Anderson, Jill Ellefson, Anthony D'Alessandro.   

Abstract

BACKGROUND: Donation after cardiac death is a method by which severely neurologically injured patients not fulfilling brain-death criteria can donate organs.
OBJECTIVE: To develop an evaluation tool that can be used to predict if a patient is a suitable candidate for donation after cardiac death.
METHODS: The University of Wisconsin Donation After Cardiac Death Evaluation Tool assigns numeric values to observable clinical parameters to yield an overall predictive score of suitability for donation after cardiac death. This evaluation tool is typically utilized in a critical care unit to evaluate patients with a severe neurological injury, who do not meet brain-death criteria, and for whom the physician and family have chosen to terminally withdraw life support. Each patient is disconnected from a ventilator and observed for up to 10 minutes. Observations are then scored to yield a prediction of suitability for donation after cardiac death.
RESULTS: Using the University of Wisconsin Donation After Cardiac Death Evaluation Tool, we were able to predict suitability for donation after cardiac death 83.7% of the time, within a 60-minute period and 74.4% of the time within a 120-minute period. The actual results using the tool were higher when clinical observations were included in the donation after cardiac death evaluation--an overall accuracy of 88.4%.

Entities:  

Mesh:

Year:  2003        PMID: 14765718     DOI: 10.1177/152692480301300405

Source DB:  PubMed          Journal:  Prog Transplant        ISSN: 1526-9248            Impact factor:   1.065


  27 in total

1.  Neurocritical care: divining death: do we have the right tools for the job?

Authors:  Matthew R Hallman; Michael J Souter
Journal:  Nat Rev Neurol       Date:  2012-06-26       Impact factor: 42.937

2.  Kidney and liver transplants from donors after cardiac death: initial experience at the London Health Sciences Centre.

Authors:  Roberto Hernandez-Alejandro; Yves Caumartin; Cameron Chent; Mark A Levstik; Douglas Quan; Norman Muirhead; Andrew A House; Vivian McAlister; Anthony M Jevnikar; Patrick P W Luke; William Wall
Journal:  Can J Surg       Date:  2010-04       Impact factor: 2.089

Review 3.  A few realistic questions raised by organ retrieval in the intensive care unit.

Authors:  Olivier Lesieur; Liliane Genteuil; Maxime Leloup
Journal:  Ann Transl Med       Date:  2017-12

Review 4.  Predicting time to death after withdrawal of life-sustaining therapy.

Authors:  Laveena Munshi; Sonny Dhanani; Sam D Shemie; Laura Hornby; Genevieve Gore; Jason Shahin
Journal:  Intensive Care Med       Date:  2015-05-06       Impact factor: 17.440

Review 5.  ICU Management of the Potential Organ Donor: State of the Art.

Authors:  Carolina B Maciel; David M Greer
Journal:  Curr Neurol Neurosci Rep       Date:  2016-09       Impact factor: 5.081

6.  Single-center study on transplantation of livers donated after cardiac death: A report of 6 cases.

Authors:  Xu-Yong Sun; Jian-Hui Dong; K E Qin; Liu-Gen Lan; Hai-Bin Li; Ying Huang; Song Cao; Zhuang-Jiang Li; Long-Jun Dai
Journal:  Exp Ther Med       Date:  2016-01-15       Impact factor: 2.447

7.  Predictors of time to death after terminal withdrawal of mechanical ventilation in the ICU.

Authors:  Colin R Cooke; David L Hotchkin; Ruth A Engelberg; Lewis Rubinson; J Randall Curtis
Journal:  Chest       Date:  2010-04-02       Impact factor: 9.410

8.  Donation after cardiac death as a strategy to increase deceased donor liver availability.

Authors:  Robert M Merion; Shawn J Pelletier; Nathan Goodrich; Michael J Englesbe; Francis L Delmonico
Journal:  Ann Surg       Date:  2006-10       Impact factor: 12.969

9.  Eligibility for organ donation following end-of-life decisions: a study performed in 43 French intensive care units.

Authors:  Olivier Lesieur; Maxime Leloup; Frédéric Gonzalez; Marie-France Mamzer
Journal:  Intensive Care Med       Date:  2014-08-05       Impact factor: 17.440

10.  Donation after cardio-circulatory death liver transplantation.

Authors:  Hieu Le Dinh; Arnaud de Roover; Abdour Kaba; Séverine Lauwick; Jean Joris; Jean Delwaide; Pierre Honoré; Michel Meurisse; Olivier Detry
Journal:  World J Gastroenterol       Date:  2012-09-07       Impact factor: 5.742

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