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Literature DB >> 147646

Haemangioma with coagulopathy: sustained response to prednisone.

J Evans, A D Batchelor, G Stark, W S Uttley.

Abstract

Two cases of giant haemangioma with thrombocytopenia are described. A satisfactory and sustained response to prednisone was achieved in respect of both coagulation abnormalities and tumour size. It is proposed that prednisone is effective by enhancement of thrombosis and reduction of fibrinolysis within the tumour, thus promoting a natural form of resolution. It is suggested that prednisone therapy should be first-choice treatment of complicated haemangiomas.

Entities: Chemical Disease

Mesh：

Substances：
Prednisone

Year: 1975 PMID： 147646 PMCID： PMC1545680 DOI： 10.1136/adc.50.10.809

Source DB: PubMed Journal: Arch Dis Child ISSN： 0003-9888 Impact factor: 3.791

12 in total

1. Giant hemangioma with thrombocytopenia. Case report with survival and sequestration studies of platelets labeled with chromium 51.

Authors: S B KONTRAS; O C GREEN; L KING; R J DURAN
Journal: Am J Dis Child Date: 1963-02

2. Effects of corticosteroids on coagulation of the blood.

Authors: S OZSOYLU; H S STRAUSS; L K DIAMOND
Journal: Nature Date: 1962-09-22 Impact factor: 49.962

3. The influence of the adrenal cortex on behavior of terminal vascular bed.

Authors: B W ZWEIFACH; E SHORR; M M BLACK
Journal: Ann N Y Acad Sci Date: 1953-07-17 Impact factor: 5.691

4. The inhibition of clot lysis by corticotrophin.

Authors: H C KWAAN; A J MCFADZEAN
Journal: Lancet Date: 1956-01-21 Impact factor: 79.321

5. Thromboembolic complications associated with ACTH and cortisone therapy.

Authors: S W COSGRIFF
Journal: J Am Med Assoc Date: 1951-11-03

6. Effect of ACTH on the erythrocyte-sedimentation rate and plasma-fibrinogen and serum-protein levels in normal persons.

Authors: G R FEARNLEY; J J BUNIM
Journal: Lancet Date: 1951-12-15 Impact factor: 79.321

Haemangioma with coagulopathy: sustained response to prednisone.

1. Giant hemangioma with thrombocytopenia. Case report with survival and sequestration studies of platelets labeled with chromium 51.

2. Effects of corticosteroids on coagulation of the blood.

3. The influence of the adrenal cortex on behavior of terminal vascular bed.

4. The inhibition of clot lysis by corticotrophin.

5. Thromboembolic complications associated with ACTH and cortisone therapy.

6. Effect of ACTH on the erythrocyte-sedimentation rate and plasma-fibrinogen and serum-protein levels in normal persons.

Review 7. Neonatal dermatology. 3. Pigmentary lesions and hemangiomas.

8. Multiple hemangiomata with thrombopenia. An unusual case with comments on steroid therapy.

9. [Angioma in infants: favorable effect of intravenous hydrocortisone].

10. Successful treatment of juvenile hemangiomas with prednisone.

1. A case of aneurysm of the jugular and mediastinal veins--radioisotopic blood pool study of venous aneurysm.