Literature DB >> 14764545

Exploring genome architecture through GOV: a WWW-based gene order visualizer.

Kishore R Sakharkar1, Vincent T K Chow.   

Abstract

MOTIVATION: The past decade has seen extension in the methods of sequence analysis from single gene based to analyzing multiple genes and proteins simultaneously. Consequently, there is a need for software tools that will allow mining of these enormous datasets at genome level effectively. A key challenge is to make them user-friendly, available to a larger community and integrate with public domain software without much hassle.
RESULTS: A web-based interactive computational tool is described for visualization and comparison of gene order from prokaryotic and selected viral genome data. Many intriguing similarities and differences in gene order of multiple genomes can be compared and revealed. The interface facilitates easy extraction of the nucleotide sequence of the gene of interest and BLAST analysis against GenBank at NCBI to provide insights into gene functions and orthologs of the gene in other species.

Mesh:

Year:  2004        PMID: 14764545     DOI: 10.1093/bioinformatics/bth046

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  1 in total

1.  GeneOrder3.0: software for comparing the order of genes in pairs of small bacterial genomes.

Authors:  Srikanth Celamkoti; Sashidhara Kundeti; Anjan Purkayastha; Raja Mazumder; Charles Buck; Donald Seto
Journal:  BMC Bioinformatics       Date:  2004-05-05       Impact factor: 3.169

  1 in total

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