| Literature DB >> 14764094 |
Avital Torres1, Malka Hochberg, Inna Pergament, Reem Smoum, Valerie Niddam, Valery M Dembitsky, Marina Temina, Inka Dor, Ovadia Lev, Morris Srebnik, Claes D Enk.
Abstract
A novel photo protective mycosporine was isolated from the lichenized ascomycete Collema cristatum. Biological activity was measured in terms of protection against UV-B induced membrane destruction and pyrimidine dimer formation in cultured human keratinocytes, and prevention of UV-B induced erythema. It was found that the pure isolated compound prevented UV-B induced cell destruction in a dose-dependent manner, that the compound partially prevented pyrimidine dimer formation and completely prevented UV-B induced erythema when applied to the skin prior to irradiation.Entities:
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Year: 2004 PMID： 14764094 DOI： 10.1111/j.1432-1033.2004.03981.x
Source DB: PubMed Journal: Eur J Biochem ISSN： 0014-2956