M Bilgrami1, L Shah. 1. Marie Stopes Society, Karachi, Pakistan.
Abstract
OBJECTIVES: To evaluate the safety, efficacy and acceptability of QS in Karachi, Pakistan. METHODS: 1000 women who had chosen sterilization during the 4-year period 1994 to 1997 inclusive were offered QS at both stationary clinics and in a mobile van at 23 sites in the outskirts of Karachi. The protocol involved transcervical insertion to the uterine fundus of 252 mg quinacrine in 7 pellets and 55 mg of ibuprofen in 3 pellets through an IUD inserter, during the proliferative phase of the menstrual cycle. Two doses were administered one month apart. A temporary method of contraception was provided for 3 cycles, usually DMPA. Follow-up was scheduled: monthly for 3 months, quarterly for 1 year and then every 6 months for 4 years. RESULTS: The crude pregnancy rate after 4 years was 2.0%. Minor complications and complaints were reported by 59% of the patients. There was one ectopic pregnancy and no major complications. CONCLUSIONS: QS was found to be safe and effective and has become the most popular method of sterilization in our area of Pakistan.
OBJECTIVES: To evaluate the safety, efficacy and acceptability of QS in Karachi, Pakistan. METHODS: 1000 women who had chosen sterilization during the 4-year period 1994 to 1997 inclusive were offered QS at both stationary clinics and in a mobile van at 23 sites in the outskirts of Karachi. The protocol involved transcervical insertion to the uterine fundus of 252 mg quinacrine in 7 pellets and 55 mg of ibuprofen in 3 pellets through an IUD inserter, during the proliferative phase of the menstrual cycle. Two doses were administered one month apart. A temporary method of contraception was provided for 3 cycles, usually DMPA. Follow-up was scheduled: monthly for 3 months, quarterly for 1 year and then every 6 months for 4 years. RESULTS: The crude pregnancy rate after 4 years was 2.0%. Minor complications and complaints were reported by 59% of the patients. There was one ectopic pregnancy and no major complications. CONCLUSIONS:QS was found to be safe and effective and has become the most popular method of sterilization in our area of Pakistan.
Authors: Jeffrey T Jensen; Carol Hanna; Shan Yao; Elizabeth Micks; Alison Edelman; Lindsay Holden; Ov D Slayden Journal: Contraception Date: 2013-11-26 Impact factor: 3.375