Literature DB >> 14762878

Predictive values for aspiration after endoscopic laser resections of malignant tumors of the hypopharynx and larynx.

Manuel Bernal-Sprekelsen1, Isabel Vilaseca-González, Jose-Luis Blanch-Alejandro.   

Abstract

BACKGROUND: CO2-laser surgery is a relatively new treatment for selected carcinomas of the upper aerodigestive tract. The purpose of our study was to evaluate prospectively the functional results for swallowing after CO2-laser resections.
METHODS: The sample was composed of 210 consecutive patients with malignancies of the larynx and hypopharynx treated with CO2 laser between February 1998 and January 2002. Endoscopic resections included all T1 and T2 tumors and selected T3 and T4 tumors. T1 glottic tumors were not included in the analysis. We assessed the need for a feeding tube and the period the tube remained in place, aspiration pneumonia, tracheotomy secondary to aspiration, the need for a permanent or temporary gastrostomy, and total laryngectomy secondary to aspiration.
RESULTS: The nasogastric feeding tube was used in 23.2% of small tumors (2.5 +/- 8.04 days) and in 63% of locally advanced tumors (13.95 +/- 22.55 days). Frequency and period of storage of the feeding tube were higher in locally advanced tumors (p=.0001). Twelve patients (5.7%) had postoperative pneumonia and 59 (28.1%) had temporary postoperative cough during oral intake. Aspiration symptoms correlated with location (p=.001) and locally advanced tumors (p=.016). Eight patients (3.8%) needed a postoperative tracheotomy for severe swallowing difficulties; six (2.9%) of them were definitive and two (0.95%) temporary. Thirteen gastrostomies (6.2%) were performed to avoid severe aspirations; five of them were definitive. The need for gastrostomy correlated significantly with location (p=.002), pT3 and pT4 tumors (p=.002), age (p=.02), and postoperative radiotherapy (p=.04). No correlation was found with the period of feeding tube (p=.38), or aspiration pneumonia (p=.24).
CONCLUSIONS: Endoscopic resection of laryngeal and hypopharyngeal tumors is associated with good recovery of deglutition. Many tracheotomies are avoided, the need for a feeding tube is usually reduced, and organ preservation is often feasible even in locally advanced tumors. Copyright 2003 Wiley Periodicals, Inc. Head Neck 26: 103-110, 2004

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Year:  2004        PMID: 14762878     DOI: 10.1002/hed.10363

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


  14 in total

1.  The learning curve in transoral laser microsurgery for malignant tumors of the larynx and hypopharynx: parameters for a levelled surgical approach.

Authors:  Manuel Bernal-Sprekelsen; José-Luis Blanch; Miguel Caballero-Borrego; Isabel Vilaseca
Journal:  Eur Arch Otorhinolaryngol       Date:  2012-09-21       Impact factor: 2.503

Review 2.  Prevention of hypopharyngeal stenosis with silastic sheeting following transoral resection.

Authors:  Jong-Lyel Roh; Yeo-Hoon Yoon
Journal:  Dysphagia       Date:  2006-04       Impact factor: 3.438

3.  Prognostic significance of surgical margins in transoral CO2 laser microsurgery for T1-T4 pharyngo-laryngeal cancers.

Authors:  Jose L Blanch; I Vilaseca; M Bernal-Sprekelsen; J J Grau; M Moragas; J Traserra-Coderch; M Caballero; F Sabater; J M Guilemany; L Alos
Journal:  Eur Arch Otorhinolaryngol       Date:  2007-05-04       Impact factor: 2.503

4.  Definitive radiotherapy for early-stage hypopharyngeal squamous cell carcinoma.

Authors:  Kaname Sato; Akira Kubota; Madoka Furukawa; Yousuke Kitani; Yuko Nakayama; Tetsuo Nonaka; Nobutaka Mizoguchi; Miho Shiomi
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-06-18       Impact factor: 2.503

5.  Function preservation using transoral laser surgery for T2-T3 glottic cancer: oncologic, vocal, and swallowing outcomes.

Authors:  Giorgio Peretti; Cesare Piazza; Francesca Del Bon; Renzo Mora; Paola Grazioli; Diego Barbieri; Stefano Mangili; Piero Nicolai
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-04-09       Impact factor: 2.503

6.  Rick factors associated with aspiration in patients with head and neck cancer.

Authors:  Soo Jin Jung; Deog Young Kim; So Young Joo
Journal:  Ann Rehabil Med       Date:  2011-12-30

7.  Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients.

Authors:  Martin Canis; Alexios Martin; Friedrich Ihler; Hendrik A Wolff; Martina Kron; Christoph Matthias; Wolfgang Steiner
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-01-10       Impact factor: 2.503

8.  Organ preservation in T4a laryngeal cancer: is transoral laser microsurgery an option?

Authors:  Martin Canis; Friedrich Ihler; Alexios Martin; Hendrik A Wolff; Christoph Matthias; Wolfgang Steiner
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-02-14       Impact factor: 2.503

9.  Complications in CO2 Laser Transoral Microsurgery for Larynx Carcinomas.

Authors:  Carlos Miguel Chiesa Estomba; Frank Alberto Betances Reinoso; Alejandra Osorio Velasquez; Jose Luis Rodriguez Fernandez; Jose Luis Fariña Conde; Carmelo Santidrian Hidalgo
Journal:  Int Arch Otorhinolaryngol       Date:  2015-12-08

10.  Oncological and complication assessment of CO2 laser-assisted endoscopic surgery for T1-T2 glottic tumours: clinical experience.

Authors:  A Galli; L Giordano; D Sarandria; D Di Santo; M Bussi
Journal:  Acta Otorhinolaryngol Ital       Date:  2016-06       Impact factor: 2.124

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