Literature DB >> 14762872

Intravascular thrombosis and thromboembolism during liver transplantation: antifibrinolytic therapy implicated?

Michael A E Ramsay1, Henry B Randall, Elizabeth C Burton.   

Abstract

This case report describes a patient who underwent orthotopic liver transplantation and developed extensive hyperacute venous and arterial intravascular thromboses and thromboemboli intraoperatively. The patient was receiving antifibrinolytic therapy with aprotinin. The safety of routine aprotinin therapy in liver transplantation is examined. The value of the thrombelastograph (TEG) as a qualitative assessment of the coagulation system is emphasized.

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Year:  2004        PMID: 14762872     DOI: 10.1002/lt.20064

Source DB:  PubMed          Journal:  Liver Transpl        ISSN: 1527-6465            Impact factor:   5.799


  6 in total

Review 1.  A benefit-risk review of systemic haemostatic agents: part 1: in major surgery.

Authors:  Ian S Fraser; Robert J Porte; Peter A Kouides; Andrea S Lukes
Journal:  Drug Saf       Date:  2008       Impact factor: 5.606

Review 2.  Requirements for transfusion and postoperative outcomes in orthotopic liver transplantation: a meta-analysis on aprotinin.

Authors:  Cun-Ming Liu; Jing Chen; Xue-Hao Wang
Journal:  World J Gastroenterol       Date:  2008-03-07       Impact factor: 5.742

3.  Antifibrinolytics in liver surgery.

Authors:  Jalpa Makwana; Saloni Paranjape; Jyotsna Goswami
Journal:  Indian J Anaesth       Date:  2010-11

4.  Epsilon-Aminocaproic Acid in Liver Transplantation: A Three-Year, Retrospective Review.

Authors:  Joseph R Whiteley; William R Hand; Harrison L Plunkett; Jason M Taylor; W David Stoll; Bethany J Wolf
Journal:  J Anesth Clin Res       Date:  2013-06-27

5.  Effect of antifibrinolytic drugs on transfusion requirement and blood loss during orthotopic liver transplantation: Results from a single center.

Authors:  Surekha Devi A; Dharmesh Kapoor; P B N Gopal; M Subrahmanyam; R S Ravichandra
Journal:  Asian J Transfus Sci       Date:  2008-07

6.  Liver transplantation: Advances and perioperative care.

Authors:  Amar Nandhakumar; Stuart A McCluskey; Coimbatore Srinivas; Tony T Chandy
Journal:  Indian J Anaesth       Date:  2012-07
  6 in total

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