Literature DB >> 14761839

Effect of treating antibody-coated sperm with chymotrypsin on pregnancy rates following IUI as compared to outcome of IVF/ICSI.

J H Check1, W Hourani, M L Check, V Graziano, E Levin.   

Abstract

Males with 100% of their sperm coated by antisperm antibody have a very small chance of achieving a pregnancy by intercourse or conventional intrauterine insemination (IUI). A previous study found that treatment of the sperm with the protein digestive enzyme chymotrypsin improved the efficacy of IUI. The present study was designed to corroborate or refute this previous study and compare efficacy to IVF with ICSI. This time the subjects were an even more difficult group with 100% of the sperm coated by autoantibodies.

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Year:  2004        PMID： 14761839

Source DB:  PubMed          Journal:  Arch Androl        ISSN： 0148-5016


  4 in total

Review 1.  Antisperm Antibody Testing: A Comprehensive Review of Its Role in the Management of Immunological Male Infertility and Results of a Global Survey of Clinical Practices.

Authors:  Sajal Gupta; Rakesh Sharma; Ashok Agarwal; Florence Boitrelle; Renata Finelli; Ala'a Farkouh; Ramadan Saleh; Taha Abo-Almagd Abdel-Meguid; Murat Gül; Birute Zilaitiene; Edmund Ko; Amarnath Rambhatla; Armand Zini; Kristian Leisegang; Shinnosuke Kuroda; Ralf Henkel; Rossella Cannarella; Ayad Palani; Chak-Lam Cho; Christopher C K Ho; Daniel Suslik Zylbersztejn; Edoardo Pescatori; Eric Chung; Fotios Dimitriadis; Germar-Michael Pinggera; Gian Maria Busetto; Giancarlo Balercia; Gianmaria Salvio; Giovanni M Colpi; Gökhan Çeker; Hisanori Taniguchi; Hussein Kandil; Hyun Jun Park; Israel Maldonado Rosas; Jean de la Rosette; Joao Paulo Greco Cardoso; Jonathan Ramsay; Juan Alvarez; Juan Manuel Corral Molina; Kareim Khalafalla; Kasonde Bowa; Kelton Tremellen; Evangelini Evgeni; Lucia Rocco; Marcelo Gabriel Rodriguez Peña; Marjan Sabbaghian; Marlon Martinez; Mohamed Arafa; Mohamed S Al-Marhoon; Nicholas Tadros; Nicolas Garrido; Osvaldo Rajmil; Pallav Sengupta; Paraskevi Vogiatzi; Parviz Kavoussi; Ponco Birowo; Raghavender Kosgi; Saleem Bani-Hani; Sava Micic; Sijo Parekattil; Sunil Jindal; Tan V Le; Taymour Mostafa; Tuncay Toprak; Yoshiharu Morimoto; Vineet Malhotra; Azin Aghamajidi; Damayanthi Durairajanayagam; Rupin Shah
Journal:  World J Mens Health       Date:  2022-01-01       Impact factor: 6.494

2.  Success rates of in vitro fertilization versus intracytoplasmic sperm injection in men with serum anti-sperm antibodies: a consecutive cohort study.

Authors:  Shao-Ming Lu; Xiao Li; Shi-Li Wang; Xiao-Li Yang; Yan-Zhen Xu; Ling-Ling Huang; Jiao-Long Liu; Fei-Fei Cai; Zi-Jiang Chen
Journal:  Asian J Androl       Date:  2019 Sep-Oct       Impact factor: 3.285

3.  Effect of mild α-chymotrypsin treatment of highly viscous semen samples on fertilization rates.

Authors:  Andreas Schallmoser; Fadi Bakjaji; Sebastian Königsberger; Julia John; Cara Färber; Elke Schmidt; Hannelore Breitenbach-Koller; Jean-Pierre Allam; Jasper Verguts; Nicole Sänger
Journal:  Transl Androl Urol       Date:  2021-01

4.  The prognostic value of seminal anti-sperm antibodies screening in men prepared for ICSI: a call to change the current antibody-directed viewpoint of sperm autoimmunity testing.

Authors:  Ahmed F El-Sherbiny; Tamer A Ali; Eman A Hassan; Amira B Mehaney; Heba A Elshemy
Journal:  Ther Adv Urol       Date:  2021-01-18
  4 in total

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