Literature DB >> 14761166

1H NMR spectroscopy with internal and external standards for the quantification of libraries.

Pablo Cironi1, Mercedes Alvarez, Fernando Albericio.   

Abstract

A convenient and easy method based on 1H NMR spectroscopy with both external and internal standards is described for the quantification of members of libraries.

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Year:  2003        PMID: 14761166     DOI: 10.1023/b:modi.0000006842.76275.a0

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  9 in total

1.  Evaluation of evaporative light-scattering detector for combinatorial library quantitation by reversed phase HPLC.

Authors:  L Fang; M Wan; M Pennacchio; J Pan
Journal:  J Comb Chem       Date:  2000 May-Jun

Review 2.  Organic synthesis in a changing world.

Authors:  Steven V Ley; Ian R Baxendale
Journal:  Chem Rec       Date:  2002       Impact factor: 6.771

3.  Solid-phase total synthesis of the pentacyclic system lamellarins U and L.

Authors:  Pablo Cironi; Ignacio Manzanares; Fernando Albericio; Mercedes Alvarez
Journal:  Org Lett       Date:  2003-08-07       Impact factor: 6.005

4.  Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries.

Authors:  C Pinilla; J R Appel; P Blanc; R A Houghten
Journal:  Biotechniques       Date:  1992-12       Impact factor: 1.993

5.  Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery.

Authors:  R A Houghten; C Pinilla; S E Blondelle; J R Appel; C T Dooley; J H Cuervo
Journal:  Nature       Date:  1991-11-07       Impact factor: 49.962

6.  A new type of synthetic peptide library for identifying ligand-binding activity.

Authors:  K S Lam; S E Salmon; E M Hersh; V J Hruby; W M Kazmierski; R J Knapp
Journal:  Nature       Date:  1991-11-07       Impact factor: 49.962

7.  Method performance and validation for quantitative analysis by (1)h and (31)p NMR spectroscopy. Applications to analytical standards and agricultural chemicals.

Authors:  G Maniara; K Rajamoorthi; S Rajan; G W Stockton
Journal:  Anal Chem       Date:  1998-12-01       Impact factor: 6.986

8.  Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid.

Authors:  H M Geysen; R H Meloen; S J Barteling
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

9.  Characterization of small combinatorial chemistry libraries by (1)H NMR. Quantitation with a convenient and novel internal standard.

Authors:  V Pinciroli; R Biancardi; N Colombo; M Colombo; V Rizzo
Journal:  J Comb Chem       Date:  2001 Sep-Oct
  9 in total

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