Literature DB >> 14760950

Alcohol and drug abuse among persons with multiple sclerosis.

C H Bombardier1, K D Blake, D M Ehde, L E Gibbons, D Moore, G H Kraft.   

Abstract

OBJECTIVE: To examine the one-month prevalence and impact of substance abuse in a large community sample of persons with multiple sclerosis (MS).
METHOD: Members of the Multiple Sclerosis Society of King County were surveyed by mail. This multifaceted health survey included questions pertaining to substance abuse. Seven hundred and thirty-nine out of 1374 potential participants (54%) returned the survey, while 708 reported a medically confirmed diagnosis of MS and provided sufficient data.
RESULTS: Fourteen per cent of the sample screened positive for possible alcohol abuse or dependence, and 7.4% reported misusing illicit drugs or prescription medications within the previous month. Possible alcohol abuse and drug misuse were associated with younger age, less severe MS related disability and being employed, as well as greater self-reported depressive symptomatology. Most persons with alcohol problems indicated interest in learning more about ways to stop or cut down.
CONCLUSIONS: Substance abuse may be present in up to 19% of this sample and contribute to high rates of depression. There may be greater risk of harm due to substance abuse in people with MS because of the potential magnification of motor and cognitive impairments. Comprehensive MS care should include substance abuse screening and advice to cut down or abstain.

Entities:  

Mesh:

Year:  2004        PMID: 14760950     DOI: 10.1191/1352458504ms989oa

Source DB:  PubMed          Journal:  Mult Scler        ISSN: 1352-4585            Impact factor:   6.312


  18 in total

Review 1.  [Coexistent depressive and anxiety disorders in epilepsy and multiple sclerosis: a challenge to neuropsychiatric practice].

Authors:  Hans-Peter Kapfhammer
Journal:  Neuropsychiatr       Date:  2014-05-20

Review 2.  Psychiatric disorders in multiple sclerosis.

Authors:  Maddalena Sparaco; Luigi Lavorgna; Simona Bonavita
Journal:  J Neurol       Date:  2019-06-13       Impact factor: 4.849

3.  Progressive multiple sclerosis and mood disorders.

Authors:  Lorena Lorefice; G Fenu; G Trincas; M F Moro; J Frau; G C Coghe; E Cocco; M G Marrosu; M G Carta
Journal:  Neurol Sci       Date:  2015-04-22       Impact factor: 3.307

Review 4.  The link between multiple sclerosis and depression.

Authors:  Anthony Feinstein; Sandra Magalhaes; Jean-Francois Richard; Blair Audet; Craig Moore
Journal:  Nat Rev Neurol       Date:  2014-08-12       Impact factor: 42.937

Review 5.  The epidemiology of alcohol consumption and multiple sclerosis: a review.

Authors:  Yu-Jie Wang; Rui Li; Jun-Wei Yan; Ya-Nan Wan; Jin-Hui Tao; Bing Chen; Xiao-Lei Huang; Guo-Jun Yang; Jing Wang; Dong-Qing Ye
Journal:  Neurol Sci       Date:  2014-11-12       Impact factor: 3.307

6.  Individual and Co-occurring SNAP Risk Factors: Smoking, Nutrition, Alcohol Consumption, and Physical Activity in People with Multiple Sclerosis.

Authors:  Julia M Balto; Ipek Ensari; Elizabeth A Hubbard; Naiman Khan; Jennifer L Barnes; Robert W Motl
Journal:  Int J MS Care       Date:  2016 Nov-Dec

7.  Alcohol shifts gut microbial networks and ameliorates a murine model of neuroinflammation in a sex-specific pattern.

Authors:  Blaine Caslin; Cole Maguire; Aditi Karmakar; Kailey Mohler; Dennis Wylie; Esther Melamed
Journal:  Proc Natl Acad Sci U S A       Date:  2019-12-02       Impact factor: 11.205

Review 8.  Modifiable comorbidities and disability in multiple sclerosis.

Authors:  Shannon Overs; Christina M Hughes; Jodie K Haselkorn; Aaron P Turner
Journal:  Curr Neurol Neurosci Rep       Date:  2012-10       Impact factor: 5.081

Review 9.  Psychiatric issues in multiple sclerosis.

Authors:  Lydia A Chwastiak; Dawn M Ehde
Journal:  Psychiatr Clin North Am       Date:  2007-12

10.  The impact of socioeconomic status on mental health and health-seeking behavior across race and ethnicity in a large multiple sclerosis cohort.

Authors:  Daniela A Pimentel Maldonado; Justin R Eusebio; Lilyana Amezcua; Eleni S Vasileiou; Ellen M Mowry; Christopher C Hemond; Raffaella Umeton Pizzolato; Idanis Berrios Morales; Irina Radu; Carolina Ionete; Kathryn C Fitzgerald
Journal:  Mult Scler Relat Disord       Date:  2021-12-05       Impact factor: 4.808

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