| Literature DB >> 14760945 |
R Bergamaschi1, S Tonietti, D Franciotta, E Candeloro, E Tavazzi, G Piccolo, A Romani, V Cosi.
Abstract
We studied repeated cerebrospinal fluids of patients with Devic's neuromyelitis optica (NMO) and multiple sclerosis (MS). Variations of oligoclonal bands (OBs) had opposite trends in the two groups. In MS, OBs were detected in 399 of 411 patients (97%) and never disappeared. In NMO, OBs were detected in three of 11 patients (27%) and always disappeared. The hypothesis that NMO and MS follow distinct pathogenetic pathways is supported by our findings, which can be useful for the differentiation of NMO from MS.Entities:
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Year: 2004 PMID: 14760945 DOI: 10.1191/1352458504ms988oa
Source DB: PubMed Journal: Mult Scler ISSN: 1352-4585 Impact factor: 6.312