Literature DB >> 1475813

Prognostic risk factors and post mortem findings in cerebral malaria in children.

O Walker1, L A Salako, A Sowunmi, J O Thomas, O Sodeine, F S Bondi.   

Abstract

We have examined the possible risk factors for poor prognosis in cerebral malaria in 61 Nigerian children in an area of high malaria transmission. The level of coma, decerebrate rigidity, hypoglycaemia, and high urea levels were indicators of poor prognosis. Pyrexia, vomiting, and anaemia did not influence prognosis. Post-mortem findings suggest gross cerebral oedema and raised intracranial pressure in 4 of 7 cases with petechial haemorrhages and small focal necrosis (Durck's granuloma).

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Year:  1992        PMID： 1475813     DOI： 10.1016/0035-9203(92)90082-n

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN： 0035-9203            Impact factor:   2.184


  17 in total

1.  Intracranial hypertension in Africans with cerebral malaria.

Authors:  C R Newton; J Crawley; A Sowumni; C Waruiru; I Mwangi; M English; S Murphy; P A Winstanley; K Marsh; F J Kirkham
Journal:  Arch Dis Child       Date:  1997-03       Impact factor: 3.791

Review 2.  Management of severe malaria in children: proposed guidelines for the United Kingdom.

Authors:  Kathryn Maitland; Simon Nadel; Andrew J Pollard; Thomas N Williams; Charles R J C Newton; Michael Levin
Journal:  BMJ       Date:  2005-08-06

Review 3.  Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria.

Authors:  Christy An Okoromah; Bosede B Afolabi; Emma Cb Wall
Journal:  Cochrane Database Syst Rev       Date:  2011-04-13

Review 4.  Cerebral malaria.

Authors:  C R Newton; T T Hien; N White
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-10       Impact factor: 10.154

5.  Dramatic changes in oxidative tryptophan metabolism along the kynurenine pathway in experimental cerebral and noncerebral malaria.

Authors:  L A Sanni; S R Thomas; B N Tattam; D E Moore; G Chaudhri; R Stocker; N H Hunt
Journal:  Am J Pathol       Date:  1998-02       Impact factor: 4.307

6.  Protective role of brain water channel AQP4 in murine cerebral malaria.

Authors:  Dominique Promeneur; Lisa Kristina Lunde; Mahmood Amiry-Moghaddam; Peter Agre
Journal:  Proc Natl Acad Sci U S A       Date:  2012-12-31       Impact factor: 11.205

7.  A quantitative analysis of the microvascular sequestration of malaria parasites in the human brain.

Authors:  K Silamut; N H Phu; C Whitty; G D Turner; K Louwrier; N T Mai; J A Simpson; T T Hien; N J White
Journal:  Am J Pathol       Date:  1999-08       Impact factor: 4.307

Review 8.  Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome.

Authors:  Richard Idro; Kevin Marsh; Chandy C John; Charles R J Newton
Journal:  Pediatr Res       Date:  2010-10       Impact factor: 3.756

9.  The neuropathology of fatal cerebral malaria in malawian children.

Authors:  Katerina Dorovini-Zis; Kristopher Schmidt; Hanh Huynh; Wenjiang Fu; Richard O Whitten; Dan Milner; Steve Kamiza; Malcolm Molyneux; Terrie E Taylor
Journal:  Am J Pathol       Date:  2011-05       Impact factor: 4.307

10.  Outcome of life-threatening malaria in African children requiring endotracheal intubation.

Authors:  Patrick Gérardin; Christophe Rogier; Amadou S Ka; Philippe Jouvencel; Bakary Diatta; Patrick Imbert
Journal:  Malar J       Date:  2007-04-30       Impact factor: 2.979
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