Literature DB >> 14758015

Synthesis of 2-N,N-dimethylaminomethyl-2,3,3a,12b-tetrahydrodibenzo-[b,f]furo[2,3-d]oxepin derivatives as potential anxiolytic agents.

Andrés Avelino Trabanco1, José Manuel Alonso, José Ignacio Andrés, José Maria Cid, Javier Fernández, Laura Iturrino, Anton Megens.   

Abstract

New synthesis approaches that have led to a series of novel tetrahydrodibenzo[b,f]furo[2,3-d]oxepin derivatives are described. According to preliminary data these novel tetracycles can be useful intermediates for the preparation of potential new therapeutic agents.

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Year:  2004        PMID: 14758015     DOI: 10.1248/cpb.52.262

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  3 in total

1.  Insights into binding modes of 5-HT2c receptor antagonists with ligand-based and receptor-based methods.

Authors:  Chunhua Lu; Fangfang Jin; Cui Li; Weihua Li; Guixia Liu; Yun Tang
Journal:  J Mol Model       Date:  2011-01-04       Impact factor: 1.810

2.  New short strategy for the synthesis of the dibenz[b,f]oxepin scaffold.

Authors:  David R R Moreno; Giorgio Giorgi; Cristian O Salas; Ricardo A Tapia
Journal:  Molecules       Date:  2013-11-29       Impact factor: 4.411

Review 3.  Microwave-Assisted Syntheses of Bioactive Seven-Membered, Macro-Sized Heterocycles and Their Fused Derivatives.

Authors:  Mohsine Driowya; Aziza Saber; Hamid Marzag; Luc Demange; Khalid Bougrin; Rachid Benhida
Journal:  Molecules       Date:  2016-08-09       Impact factor: 4.411

  3 in total

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