| Literature DB >> 14757043 |
Gorka Orive1, Rose Maria Hernández, Alicia Rodríguez Gascón, Riccardo Calafiore, Thomas Ming Swi Chang, Paul de Vos, Gonzalo Hortelano, David Hunkeler, Igor Lacík, José Luis Pedraz.
Abstract
Cell microencapsulation continues to hold significant promise for biotechnology and medicine. The controlled, and continuous, delivery of therapeutic products to the host by immunoisolated cells is a potentially cost-effective method to treat a wide range of diseases. Although there are several issues that need to be addressed, including capsule manufacture, properties and performance, in the past few years, a stepwise analysis on the essential obstacles and limitations has brought the whole technology closer to a realistic proposal for clinical application. This paper summarizes the current situation in the cell encapsulation field and discusses the main events that have occurred along the way.Mesh：
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Year: 2004 PMID： 14757043 DOI： 10.1016/j.tibtech.2003.11.004
Source DB: PubMed Journal: Trends Biotechnol ISSN： 0167-7799 Impact factor: 19.536