Literature DB >> 14756655

Squamous cell carcinoma of the nail unit with evidence of bony involvement: a multidisciplinary approach to resection and reconstruction.

S Ray Peterson1, Ernest G Layton, Aaron K Joseph.   

Abstract

BACKGROUND: Squamous cell carcinoma (SCC) of the nail bed is a rare disorder that is often misdiagnosed for years before definitive diagnosis with biopsy. Proper evaluation of this carcinoma includes radiographic evaluation for bony involvement of the phalanges of the affected digit. If bony involvement is evident by x-ray, amputation of the distal phalanx or the affected digit is warranted. Mohs micrographic surgery of the affected nail unit is advantageous in preserving vital tissue for reconstruction after phalangeal amputation by a hand surgeon, thus maximizing preservation of the densely innervated tissue from the volar finger pulp. This approach may maximize functional capacity of the reconstructed digit.
OBJECTIVE: To describe a multidisciplinary approach to resection, amputation, and reconstruction of digits with SCC of the nail bed.
METHODS: This is a description of three cases and a review of the pertinent medical literature.
RESULTS: Three SCCs of the nail bed were excised with Mohs micrographic surgery, preserving the volar pulp and skin of the distal finger. The patients were then referred for distal phalanx amputation and reconstruction by a hand surgeon. All patients remained disease free with acceptable function of the reconstructed digits at 15, 17, and 38 months of follow-up.
CONCLUSION: Although uncommon, SCC of the nail bed must be considered in all nails with chronic disease. Preoperative evaluation should include hand radiographs in search of bony involvement. Tissue-sparing excision combined with distal amputation of the affected phalanx and reconstruction of the digit using spared tissue may maximize hand and digit function.

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Mesh:

Year:  2004        PMID: 14756655     DOI: 10.1111/j.1524-4725.2004.30068.x

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  5 in total

Review 1.  Radiological Imaging in Nail Unit Disorders (Part I) - Modalities Used.

Authors:  Chander Grover; Shikha Bansal; Ameeta Varma; Deepak Jakhar
Journal:  Indian Dermatol Online J       Date:  2022-06-24

2.  Squamous cell carcinoma of the nail unit.

Authors:  Michela Starace; Aurora Alessandrini; Emi Dika; Bianca Maria Piraccini
Journal:  Dermatol Pract Concept       Date:  2018-07-31

3.  Squamous Cell Carcinoma of the Nail Unit After Trauma: A Case Report.

Authors:  Wen Xu; Dandan Mao; Guangdong Wen
Journal:  Clin Cosmet Investig Dermatol       Date:  2022-08-24

4.  Evaluation of a distal dorsal thumb lesion.

Authors:  Lily Daniali; Kodi Azari
Journal:  Eplasty       Date:  2013-04-12

Review 5.  A single centre experience of squamous cell carcinoma of the upper limb requiring digital or hand amputation and review of literature.

Authors:  Leela Sayed; Avinash K Deodhar; Reena Agarwal
Journal:  JPRAS Open       Date:  2019-01-09
  5 in total

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