Literature DB >> 1475552

Asthmatic drugs and competitive sport. An update.

A R Morton1, K D Fitch.   

Abstract

Almost all asthmatics are prone to asthma triggered by moderate to severe exercise. Fortunately there are a number of pharmaceutical agents now available which can prevent and/or reverse exercise-induced asthma (EIA) and allow many asthmatics to participate in vigorous physical activities with minimum respiratory disadvantage. Regular exercise is an accepted part of the management of asthma and EIA can now be controlled so successfully that a number of elite sportspersons, in almost all types of sporting events, are asthmatic. This control of EIA, which is essential if asthmatics are to participate safely, requires that the patient and his/her doctor initiate a strategy to manage the disease during sport and other physical activities. In recent years the mortality and morbidity from asthma have been increasing and this has indicated the need to improve patient care. One of the most important innovations aiming to improve the control and treatment of asthma has been the recent development of the 6 point asthma management plan which is a strategy to simplify and optimise the long term management of asthma. It aims to improve the quality of life of most asthmatics and more importantly, prevent deaths due to asthma. Because antidoping controls operate in many high performance sports it is essential that the EIA management plan rely on those medications which are permitted. The list of allowable drugs is in continual flux as new ones are added and others are challenged on the grounds of possible ergogenicity. All aerosol beta 2-agonists except fenoterol, the khellin derivatives, theophylline, ipratropium bromide and the aerosol corticosteroids are currently permitted. Some nonasthmatic athletes who are aware of the improved performance of asthmatic athletes when using pre-exercise medication have been known to take antiasthma medication in the hope that it might improve their performance. Current evidence indicates, however, that the permitted medications are not ergogenic and do not give the asthmatic any advantage over the nonasthmatic athlete but merely removes the respiratory disadvantage under which he/she competes.

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Year:  1992        PMID: 1475552     DOI: 10.2165/00007256-199214040-00002

Source DB:  PubMed          Journal:  Sports Med        ISSN: 0112-1642            Impact factor:   11.136


  39 in total

1.  Study of theophylline plasma levels after oral administration of new theophylline compounds.

Authors:  M TURNER-WARWICK
Journal:  Br Med J       Date:  1957-07-13

2.  The effects of theophylline on the physical performance and work capacity of well-trained athletes.

Authors:  A R Morton; C A Scott; K D Fitch
Journal:  J Allergy Clin Immunol       Date:  1989-01       Impact factor: 10.793

3.  Rational intravenous doses of theophylline.

Authors:  P A Mitenko; R I Ogilvie
Journal:  N Engl J Med       Date:  1973-09-20       Impact factor: 91.245

4.  Corticosteroids in treatment of chronic asthma.

Authors:  S D Walsh; I W Grant
Journal:  Br Med J       Date:  1966-10-01

5.  Increased ventilation caused by improved diaphragmatic efficiency during aminophylline infusion.

Authors:  M Aubier; D Murciano; N Viires; Y Lecocguic; S Palacios; R Pariente
Journal:  Am Rev Respir Dis       Date:  1983-02

6.  Perception of asthma.

Authors:  A R Rubinfeld; M C Pain
Journal:  Lancet       Date:  1976-04-24       Impact factor: 79.321

7.  Nedocromil sodium and exercise induced asthma.

Authors:  N Chudry; F Correa; M Silverman
Journal:  Arch Dis Child       Date:  1987-04       Impact factor: 3.791

8.  Effect of nebulised salbutamol on maximal exercise performance in men with mild asthma.

Authors:  W Freeman; G E Packe; R M Cayton
Journal:  Thorax       Date:  1989-11       Impact factor: 9.139

9.  Aminophylline improves diaphragmatic contractility.

Authors:  M Aubier; A De Troyer; M Sampson; P T Macklem; C Roussos
Journal:  N Engl J Med       Date:  1981-07-30       Impact factor: 91.245

10.  Other pharmacologic agents that may affect bronchial hyperreactivity.

Authors:  C T Furukawa
Journal:  J Allergy Clin Immunol       Date:  1984-05       Impact factor: 10.793

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  6 in total

Review 1.  The rush to adrenaline: drugs in sport acting on the beta-adrenergic system.

Authors:  E Davis; R Loiacono; R J Summers
Journal:  Br J Pharmacol       Date:  2008-06       Impact factor: 8.739

Review 2.  Drugs and sport. Research findings and limitations.

Authors:  P M Clarkson; H S Thompson
Journal:  Sports Med       Date:  1997-12       Impact factor: 11.136

3.  Reduction of exercise-induced asthma in children by short, repeated warm ups.

Authors:  C de Bisschop; H Guenard; P Desnot; J Vergeret
Journal:  Br J Sports Med       Date:  1999-04       Impact factor: 13.800

4.  The effect of salbutamol on performance in endurance cyclists.

Authors:  S R Norris; S R Petersen; R L Jones
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1996

Review 5.  Exercise-induced asthma and anaphylaxis.

Authors:  D O Hough; K L Dec
Journal:  Sports Med       Date:  1994-09       Impact factor: 11.136

6.  Asthma medications: basic pharmacology and use in the athlete.

Authors:  J E Houglum
Journal:  J Athl Train       Date:  2000-04       Impact factor: 2.860

  6 in total

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