Literature DB >> 14755375

Chronic myeloid leukemia with an e13a3 BCR-ABL fusion: benign course responsive to imatinib with an RT-PCR advisory.

David S Snyder1, Ross McMahon, Sandra R Cohen, Marilyn L Slovak.   

Abstract

A case of a patient with chronic myeloid leukemia whose cells expressed an e13a3 (b2a3) variant BCR-ABL p210 mRNA is presented. The variant splice was detected by a qualitative reverse transcriptase polymerase chain reaction using primers complementary to BCR exon 13 (b2) and ABL exon 3 (a3). The patient responded well to imatinib and achieved a complete cytogenetic response. Copyright 2004 Wiley-Liss, Inc.

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Year:  2004        PMID： 14755375     DOI： 10.1002/ajh.10456

Source DB:  PubMed          Journal:  Am J Hematol        ISSN： 0361-8609            Impact factor:   10.047


  9 in total

1.  A chronic myeloid leukemia patient with atypical karyotype and BCR-ABL e13a3 transcript caused by complex chromosome rearrangement.

Authors:  Masayoshi Masuko; Tatsuo Furukawa; Takashi Abe; Reiko Wada; Soichi Maruyama; Toshiki Kitajima; Yasuhiko Shibasaki; Ken Toba; Masahiko Okada; Yoshifusa Aizawa
Journal:  Int J Hematol       Date:  2009-06-30       Impact factor: 2.490

2.  A rare e14a3 BCR/ABL fusion transcript in acute lymphoblastic leukemia patient treated with CAR-modified T-cell therapy.

Authors:  Haodong Cai; Li Yang; Kefeng Shen; Wei Zhang; Jie Xiong; Meilan Zhang; Xia Mao; Ying Wang; Min Xiao
Journal:  Oncol Lett       Date:  2017-12-13       Impact factor: 2.967

3.  Rapid decline of Philadelphia-positive metaphases after nilotinib treatment in a CML patient expressing a rare e14a3 BCR-ABL1 fusion transcript: A case report.

Authors:  Michele Massimino; Stefania Stella; Elena Tirrò; Maria Letizia Consoli; Maria Stella Pennisi; Adriana Puma; Silvia Rita Vitale; Chiara Romano; Valentina Zammit; Fabio Stagno; Francesco Di Raimondo; Livia Manzella
Journal:  Oncol Lett       Date:  2019-07-04       Impact factor: 2.967

4.  Molecular response to imatinib in chronic myeloid leukaemia with a variant e13a3 BCR-ABL1 fusion.

Authors:  Sarah L McCarron; Stephen E Langabeer; Karen Bolger; Karl Haslam; Mireille Crampe; Johanna Kelly; Ruth Morrell
Journal:  Med Oncol       Date:  2015-01-13       Impact factor: 3.064

5.  A rare chronic myeloid leukemia case with Philadelphia chromosome, BCR-ABL e13a3 transcript and complex translocation involving four different chromosomes.

Authors:  Walid Al Achkar; Abdulsamad Wafa; Bashar Yousef Ali; Marina Manvelyan; Thomas Liehr
Journal:  Oncol Lett       Date:  2010-09-01       Impact factor: 2.967

Review 6.  A variant transcript, e1a3, of the minor BCR-ABL fusion gene in acute lymphoblastic leukemia: case report and review of the literature.

Authors:  Shinya Fujisawa; Satoki Nakamura; Kensuke Naito; Masahide Kobayashi; Kazunori Ohnishi
Journal:  Int J Hematol       Date:  2008-02-06       Impact factor: 2.490

7.  A novel BCR-ABL1 fusion gene with genetic heterogeneity indicates a good prognosis in a chronic myeloid leukemia case.

Authors:  Fen Zhou; Runming Jin; Yu Hu; Heng Mei
Journal:  Mol Cytogenet       Date:  2017-05-19       Impact factor: 2.009

Review 8.  Dasatinib and Azacitidine Followed by Haploidentical Stem Cell Transplant for Chronic Myeloid Leukemia with Evolving Myelodysplasia: A Case Report and Review of Treatment Options.

Authors:  Fabian Lang; Lydia Wunderle; Heike Pfeifer; Susanne Schnittger; Gesine Bug; Oliver G Ottmann
Journal:  Am J Case Rep       Date:  2017-10-16

9.  Chronic myeloid leukemia with a rare fusion transcript, b2a3 (e13a3) BCR-ABL1: A report of four cases from India.

Authors:  Sudha Sazawal; Sunita Chhikara; Kanwaljeet Singh; Rekha Chaubey; Manoranjan Mahapatra; Tulika Seth; Renu Saxena
Journal:  South Asian J Cancer       Date:  2019 Apr-Jun
  9 in total

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