Literature DB >> 14755360

[Counselling, genetic testing and prevention in women with hereditary breast- and ovarian cancer. Interdisciplinary recommendations of the consortium "Hereditary Breast- and Ovarian Cancer" of the German Cancer AiD].

R Schmutzler1, B Schlegelberger, A Meindl, W-D Gerber, M Kiechle.   

Abstract

Women with familial predisposition for breast and ovarian cancer represent a small group of patients with very high risk for developing breast and/ or ovarian cancer before the age of 50 years. The individual breast cancer risk can be assessed by genetic counselling and can be specified by genetic diagnostics. As part of the gynaecological consultation, adequate preventive measures are offered. Psycho-oncological counselling may help in decision making. For hereditary carcinomas, counselling is still not considered as a routine medical care, even though basic and routine preventive measures are insufficient for this group of high risk patients. Within the last years, 12 specialized centres in Germany have developed a patient care concept for women with a familial risk for breast and ovarian cancer. Establishment of these centres for familial breast and ovarian cancer and use of evidence-based medical care was initiated in a nationwide interdisciplinary joint research project and supported by the German Cancer AiD. These measures were integrated in a quality assurance concept for structure, process and result optimization. Thus, all requirements for introducing these services into routine patient management have been fulfilled.

Entities:  

Mesh:

Year:  2003        PMID: 14755360     DOI: 10.1055/s-2003-44815

Source DB:  PubMed          Journal:  Zentralbl Gynakol        ISSN: 0044-4197


  6 in total

1.  Identification of Novel Susceptibility Genes for Breast Cancer - Genome-Wide Association Studies or Evaluation of Candidate Genes?

Authors:  Alfons Meindl
Journal:  Breast Care (Basel)       Date:  2009-04-24       Impact factor: 2.860

2.  Genetic testing for familial/hereditary breast cancer-comparison of guidelines and recommendations from the UK, France, the Netherlands and Germany.

Authors:  Dorothea Gadzicki; D Gareth Evans; Hilary Harris; Claire Julian-Reynier; Irmgard Nippert; Jörg Schmidtke; Aad Tibben; Christi J van Asperen; Brigitte Schlegelberger
Journal:  J Community Genet       Date:  2011-03-02

3.  Detected, yet not Diagnosed - Breast Cancer Screening with MRI Mammography in High-Risk Women.

Authors:  Joerg Heil; Elena Czink; Anne Schipp; Christof Sohn; Hans Junkermann; Michael Golatta
Journal:  Breast Care (Basel)       Date:  2012-06-22       Impact factor: 2.860

4.  [The genetic revolution-impact on therapy and prevention].

Authors:  P Propping; S Aretz
Journal:  Internist (Berl)       Date:  2004-06       Impact factor: 0.743

Review 5.  Breast cancer susceptibility: current knowledge and implications for genetic counselling.

Authors:  Tim Ripperger; Dorothea Gadzicki; Alfons Meindl; Brigitte Schlegelberger
Journal:  Eur J Hum Genet       Date:  2008-12-17       Impact factor: 4.246

6.  Psychological Distress and Coping Ability of Women at High Risk of Hereditary Breast and Ovarian Cancer before Undergoing Genetic Counseling-An Exploratory Study from Germany.

Authors:  Beate Vajen; Magdalena Rosset; Hannah Wallaschek; Eva Baumann; Brigitte Schlegelberger
Journal:  Int J Environ Res Public Health       Date:  2021-04-19       Impact factor: 3.390

  6 in total

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