Trace elements supplementation: recent advances and perspectives.

Supplementation of essential trace elements has become an increasingly important field of research in modern pharmacology. The present review presents general aspects related to the essentiality of inorganic systems in living organisms, followed by a detailed discussion of the supplementation of iron, copper, zinc, chromium, selenium, magnesium and some other minor trace elements. Some recent advances in this field as well as future challenges and perspectives are also discussed.