Literature DB >> 14752272

Polycomb group proteins in cell cycle progression and cancer.

Diego Pasini1, Adrian P Bracken, Kristian Helin.   

Abstract

Epigenetic deregulation of gene expression is emerging as key mechanism in tumorigenesis. Deregulated activity of the chromatin remodeling Polycomb Repressive Complex 2 (PRC2) has recently been shown to be a frequent event in human tumors. Here we discuss these findings and speculate on the role of the PRC2 complex in controlling gene expression during normal cellular proliferation and cancer development.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 14752272

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  40 in total

Review 1.  Identification of driver and passenger DNA methylation in cancer by epigenomic analysis.

Authors:  Satish Kalari; Gerd P Pfeifer
Journal:  Adv Genet       Date:  2010       Impact factor: 1.944

2.  Dimerization of a viral SET protein endows its function.

Authors:  Hua Wei; Ming-Ming Zhou
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-11       Impact factor: 11.205

3.  Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions.

Authors:  Adrian P Bracken; Nikolaj Dietrich; Diego Pasini; Klaus H Hansen; Kristian Helin
Journal:  Genes Dev       Date:  2006-04-17       Impact factor: 11.361

4.  Mutations in the extra sex combs and Enhancer of Polycomb genes increase homologous recombination in somatic cells of Drosophila melanogaster.

Authors:  Angela M Holmes; Kelly A Weedmark; Gregory B Gloor
Journal:  Genetics       Date:  2006-02-01       Impact factor: 4.562

5.  lncRNAs combine and crosstalk with NSPc1 in ATRA-induced differentiation of U87 glioma cells.

Authors:  Zhikong Liang; Yuliang Wang; Hui Li; Yi Sun; Yanhua Gong
Journal:  Oncol Lett       Date:  2019-04-15       Impact factor: 2.967

6.  Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression.

Authors:  Bin Bao; Shadan Ali; Sanjeev Banerjee; Zhiwei Wang; Farah Logna; Asfar S Azmi; Dejuan Kong; Aamir Ahmad; Yiwei Li; Subhash Padhye; Fazlul H Sarkar
Journal:  Cancer Res       Date:  2011-11-22       Impact factor: 12.701

7.  Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity.

Authors:  Diego Pasini; Adrian P Bracken; Michael R Jensen; Eros Lazzerini Denchi; Kristian Helin
Journal:  EMBO J       Date:  2004-09-23       Impact factor: 11.598

8.  Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells.

Authors:  Manjari Dimri; Prashant V Bommi; Anagh A Sahasrabuddhe; Janardan D Khandekar; Goberdhan P Dimri
Journal:  Carcinogenesis       Date:  2009-12-07       Impact factor: 4.944

9.  Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion.

Authors:  Carmela Calés; Mónica Román-Trufero; Leticia Pavón; Iván Serrano; Teresa Melgar; Mitsuhiro Endoh; Claudia Pérez; Haruhiko Koseki; Miguel Vidal
Journal:  Mol Cell Biol       Date:  2007-11-26       Impact factor: 4.272

Review 10.  Genetic and epigenetic alterations in breast cancer: what are the perspectives for clinical practice?

Authors:  Alfredo Fucito; Chiara Lucchetti; Antonio Giordano; Gaetano Romano
Journal:  Int J Biochem Cell Biol       Date:  2007-10-23       Impact factor: 5.085
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.