Literature DB >> 14751966

Gene Unscrambler for detangling scrambled genes in ciliates.

Andre R O Cavalcanti1, Laura F Landweber.   

Abstract

UNLABELLED: Scrambled genes are surprisingly common in some species of ciliates. Until now there was no software available to analyze automatically these genes. We present here a program that can automatically align the macronuclear and micronuclear forms of a gene, outputting the location of the macronuclear destined segments and pointer sequences. AVAILABILITY: A web version of the program is available free of charge and can be accessed at http://oxytricha.princeton.edu/GeneUnscrambler.htm

Mesh:

Year:  2004        PMID: 14751966     DOI: 10.1093/bioinformatics/bth003

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  4 in total

1.  The evolutionary origin of a complex scrambled gene.

Authors:  Wei-Jen Chang; Paul D Bryson; Han Liang; Mann Kyoon Shin; Laura F Landweber
Journal:  Proc Natl Acad Sci U S A       Date:  2005-10-10       Impact factor: 11.205

2.  Interconversion of germline-limited and somatic DNA in a scrambled gene.

Authors:  Matthias Möllenbeck; Andre R O Cavalcanti; Franziska Jönsson; Hans J Lipps; Laura F Landweber
Journal:  J Mol Evol       Date:  2006-06-03       Impact factor: 2.395

3.  MDS_IES_DB: a database of macronuclear and micronuclear genes in spirotrichous ciliates.

Authors:  Andre R O Cavalcanti; Thomas H Clarke; Laura F Landweber
Journal:  Nucleic Acids Res       Date:  2005-01-01       Impact factor: 16.971

4.  The pathway to detangle a scrambled gene.

Authors:  Matthias Möllenbeck; Yi Zhou; Andre R O Cavalcanti; Franziska Jönsson; Brian P Higgins; Wei-Jen Chang; Stefan Juranek; Thomas G Doak; Grzegorz Rozenberg; Hans J Lipps; Laura F Landweber
Journal:  PLoS One       Date:  2008-06-04       Impact factor: 3.240

  4 in total

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