BACKGROUND: We describe a case of convexity meningioma en plaque (MEP) invading the skull and scalp with diffuse massive hyperostosis, presenting striking radiological findings. CASE DESCRIPTION: A 48-year-old woman was admitted to our hospital with headache, general fatigue, diplopia, and blurred vision. A skull X-ray film, computed tomography (CT), and 3-dimensional CT demonstrated diffuse significant hyperostosis and sclerosis in the cranial vault. Magnetic resonance (MR) imaging revealed a frontoparietal, well-enhanced extra-axial mass lesion, which is compatible with findings of MEP. The tumor was partially resected. Histological examination revealed massive tumor invasion into the dura mater, hyperostotic skull, and scalp. CONCLUSION: Hyperostosis is frequently observed in MEP, although there has been no report of a case of MEP such as ours demonstrating diffuse tumor extension and diffuse hyperostosis. Analyzing the CT finding of hyperostotic bone is useful for differentiation of MEP from other diseases that include a hyperostotic condition.
BACKGROUND: We describe a case of convexity meningioma en plaque (MEP) invading the skull and scalp with diffuse massive hyperostosis, presenting striking radiological findings. CASE DESCRIPTION: A 48-year-old woman was admitted to our hospital with headache, general fatigue, diplopia, and blurred vision. A skull X-ray film, computed tomography (CT), and 3-dimensional CT demonstrated diffuse significant hyperostosis and sclerosis in the cranial vault. Magnetic resonance (MR) imaging revealed a frontoparietal, well-enhanced extra-axial mass lesion, which is compatible with findings of MEP. The tumor was partially resected. Histological examination revealed massive tumor invasion into the dura mater, hyperostotic skull, and scalp. CONCLUSION:Hyperostosis is frequently observed in MEP, although there has been no report of a case of MEP such as ours demonstrating diffuse tumor extension and diffuse hyperostosis. Analyzing the CT finding of hyperostotic bone is useful for differentiation of MEP from other diseases that include a hyperostotic condition.
Authors: Kim M Keppler-Noreuil; Eva H Baker; Julie C Sapp; Marjorie J Lindhurst; Leslie G Biesecker Journal: Am J Med Genet A Date: 2016-08-23 Impact factor: 2.802
Authors: H Uetani; M Akter; T Hirai; Y Shigematsu; M Kitajima; Y Kai; S Yano; H Nakamura; K Makino; M Azuma; R Murakami; Y Yamashita Journal: AJNR Am J Neuroradiol Date: 2012-10-18 Impact factor: 3.825
Authors: Baha'eddin A Muhsen; Abdelmajid I Aljariri; Hasan Hashem; Qasem Alzoubi; Nasim Sarhan; Maysa Al-Hussaini; Abdellatif Al Mousa Journal: Ann Med Surg (Lond) Date: 2022-01-28
Authors: Theresa A Elder; Hana Yokoi; A Jessey Chugh; Carlito Lagman; Osmond Wu; Christina Huang Wright; Abhishek Ray; Nicholas Bambakidis Journal: J Neurol Surg B Skull Base Date: 2019-12-23