Literature DB >> 14750578

Treatment duration of reversal reaction: a reappraisal. Back to the past.

Ben Naafs1.   

Abstract

In this paper, earlier data on the length of prednisolone treatment are re-examined. Based on those data and supported by the literature and the author's own observations, it can be concluded that type I leprosy reaction should be treated with prednisolone for a longer period than the 12 weeks, advised by the WHO. The paper also warns against silent nerve damage that may occur when prednisolone is discontinued early.

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Year:  2003        PMID： 14750578

Source DB:  PubMed          Journal:  Lepr Rev        ISSN： 0305-7518            Impact factor:   0.537


  6 in total

Review 1.  The continuing challenges of leprosy.

Authors:  D M Scollard; L B Adams; T P Gillis; J L Krahenbuhl; R W Truman; D L Williams
Journal:  Clin Microbiol Rev       Date:  2006-04       Impact factor: 26.132

2.  A phase two randomised controlled double blind trial of high dose intravenous methylprednisolone and oral prednisolone versus intravenous normal saline and oral prednisolone in individuals with leprosy type 1 reactions and/or nerve function impairment.

Authors:  Stephen L Walker; Peter G Nicholls; Sushmita Dhakal; Rachel A Hawksworth; Murdo Macdonald; Kishori Mahat; Shudan Ruchal; Sushma Hamal; Deanna A Hagge; Kapil D Neupane; Diana N J Lockwood
Journal:  PLoS Negl Trop Dis       Date:  2011-04-12

3.  Paracoccidioidomycosis: epidemiological, clinical, diagnostic and treatment up-dating.

Authors:  Silvio Alencar Marques
Journal:  An Bras Dermatol       Date:  2013 Sep-Oct       Impact factor: 1.896

4.  Autophagy Impairment Is Associated With Increased Inflammasome Activation and Reversal Reaction Development in Multibacillary Leprosy.

Authors:  Mayara Garcia de Mattos Barbosa; Bruno Jorge de Andrade Silva; Tayná Quintella Assis; Rhana Berto da Silva Prata; Helen Ferreira; Priscila Ribeiro Andrade; Jéssica Araújo da Paixão de Oliveira; Gilberto Marcelo Sperandio da Silva; José Augusto da Costa Nery; Euzenir Nunes Sarno; Roberta Olmo Pinheiro
Journal:  Front Immunol       Date:  2018-06-04       Impact factor: 7.561

Review 5.  Treatment and Evaluation Advances in Leprosy Neuropathy.

Authors:  Gigi J Ebenezer; David M Scollard
Journal:  Neurotherapeutics       Date:  2021-11-19       Impact factor: 7.620

6.  Enlarging plaque on the face with enlarged supraorbital nerve.

Authors:  Cesare Massone; Andrea Clapasson; Sergio Gennaro; Enrico Nunzi
Journal:  Dermatol Pract Concept       Date:  2013-01-31
  6 in total

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