OBJECTIVES: This study was undertaken to develop a three-dimensional (3D) ultrasound method of measuring fetal brain volume. STUDY DESIGN: Serial 3D sonographic measurements of fetal brain volume were made in 68 normal singleton pregnancies at 18 to 34 weeks of gestation. A comparison was made with fetal brain volume estimates from two-dimensional (2D) sonographic measurement of head circumference and published postmortem fetal brain weights. RESULTS: Coefficient of variation for fetal brain volume (3D) caused by differences between repeated tests was 10.2% and between analyses of the same recorded volume 2.2%. Median brain volume increases from 34 mL at 18 weeks to 316 mL at 34 weeks. Median brain weight represented approximately 15% of total fetal weight. The 3D ultrasound-derived brain weight is larger than postmortem brain weight. However, this is not so for brain weight derived from total fetal weight at autopsy. A good agreement between 3D and 2D brain volume was found. CONCLUSION: Sonographic measurement of fetal brain volume demonstrated an acceptable intraobserver variability and a nearly 10-fold increase during the second half of gestation.
OBJECTIVES: This study was undertaken to develop a three-dimensional (3D) ultrasound method of measuring fetal brain volume. STUDY DESIGN: Serial 3D sonographic measurements of fetal brain volume were made in 68 normal singleton pregnancies at 18 to 34 weeks of gestation. A comparison was made with fetal brain volume estimates from two-dimensional (2D) sonographic measurement of head circumference and published postmortem fetal brain weights. RESULTS: Coefficient of variation for fetal brain volume (3D) caused by differences between repeated tests was 10.2% and between analyses of the same recorded volume 2.2%. Median brain volume increases from 34 mL at 18 weeks to 316 mL at 34 weeks. Median brain weight represented approximately 15% of total fetal weight. The 3D ultrasound-derived brain weight is larger than postmortem brain weight. However, this is not so for brain weight derived from total fetal weight at autopsy. A good agreement between 3D and 2D brain volume was found. CONCLUSION: Sonographic measurement of fetal brain volume demonstrated an acceptable intraobserver variability and a nearly 10-fold increase during the second half of gestation.
Authors: Ali Gholipour; Judy A Estroff; Carol E Barnewolt; Susan A Connolly; Simon K Warfield Journal: Int J Comput Assist Radiol Surg Date: 2010-07-13 Impact factor: 2.924
Authors: Liqun Sun; Christopher K Macgowan; John G Sled; Shi-Joon Yoo; Cedric Manlhiot; Prashob Porayette; Lars Grosse-Wortmann; Edgar Jaeggi; Brian W McCrindle; John Kingdom; Edward Hickey; Steven Miller; Mike Seed Journal: Circulation Date: 2015-03-11 Impact factor: 29.690
Authors: Bahiyah Al Nafisi; Joshua F P van Amerom; Jonathan Forsey; Edgar Jaeggi; Lars Grosse-Wortmann; Shi-Joon Yoo; Christopher K Macgowan; Mike Seed Journal: J Cardiovasc Magn Reson Date: 2013-07-27 Impact factor: 5.364